Search Results - zhongwei+liu

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Label–free, high-throughput holographic screening and enumeration of tumor cells in blood

Technology SummaryCirculating tumor cells (CTCs) are cells that have entered the peripheral blood of cancer patients after having left primary or metastatic tumors. Identifying the presence and assessing the characteristics of these CTCs through liquid biopsies has shown great promise for improving cancer patient care by enabling early cancer detection.Current...

Published: 11/29/2018 | Inventor(s): Siva Vanapalli, Dhananjay Singh, Wei Li, Caroline Ahrens

Keywords(s):

Category(s): Assay, Cancer Diagnostics, Device, Life Sciences, Medical Device, Medical Diagnostic, Pharmaceutical, Therapeutics

Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells

Technology SummaryThe use of EGFR inhibitors in the treatment of NSCLC is well established, even being used as a first-line treatment for certain drugs like Gefitinib and Osimertinib. However, eventual drug-resistance by the tumor to these treatments remains a problem. This technology showcases how CRM1 inhibitor Leptomycin B can potentiate the EGFR...

Published: 9/17/2018 | Inventor(s): Weimin Gao, Zhongwei Liu

Keywords(s):

Category(s): Cancer Therapeutics