<?xml version="1.0" encoding="utf-8"?><rss version="2.0"><channel><title>Latest technologies from Texas Tech Office of Technology Commercialization</title><link>http://ttusorc.technologypublisher.com</link><description>Be the first to know about the latest inventions and technologies available from Texas Tech Office of Research Commercialization</description><language>en-US</language><pubDate>Tue, 07 Apr 2026 20:36:23 GMT</pubDate><lastBuildDate>Tue, 16 Oct 2018 09:27:20 GMT</lastBuildDate><docs>http://blogs.law.harvard.edu/tech/rss</docs><webMaster>david.mcclure@ttu.edu</webMaster><copyright>Copyright 2026, Texas Tech Office of Technology Commercialization</copyright><item><title>Three Dimensional Kinetic Generator</title><caseId>D-1321</caseId><link>http://ttusorc.technologypublisher.com/technology/29015</link><description>In today's society, almost everyone always has a mobile phone or electronic device on him or her. These devices have become central to people's everyday lives as they are used both socially and professionally. One of the main issues with these portable devices is they are known to quickly run out of energy or battery life. This can become a nuisance, as recharging mobile/portable devices typically requires users to go out of their way to find a power source. Current methods of charging mobile/portable devices are not typically mobile friendly. The most common source of energy is a wall outlet ...</description><pubDate>Tue, 16 Oct 2018 09:27:20 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/29015</guid></item><item><title>Microdevice for Cell Separation Based on Activation Phenotype</title><caseId>D-1072</caseId><link>http://ttusorc.technologypublisher.com/technology/28979</link><description><![CDATA[This technology consists of a microdevice that separates blood cells based on differences in antigen expression. Cells of the same phenotype are separated based on their activation levels during infection and resting, thus enabling the microdevice to provide differential cell counts as a diagnostic tool for infections and inflammations.&nbsp; &nbsp;Reference Number: D-1072&nbsp;Market Applications:Pharmaceuticals/Health CareIn Vitro Diagnostics&nbsp;Features, Benefits &amp; Advantages:Provides differential cell counts in a short-time spanAllows for the quick identification of infections, parti...]]></description><pubDate>Thu, 11 Oct 2018 08:44:43 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28979</guid></item><item><title>Selectable stem cell modification for anti-HIV gene therapy using transient cell surface marking of modified cells using Modified CD4 molecule (CD4mod)</title><caseId>D-1356</caseId><link>http://ttusorc.technologypublisher.com/technology/28978</link><description><![CDATA[Green fluorescent protein (GFP) is a common in vitro cell surface marker, however, when incorporated in vivo, it can lead to unwanted immune responses. This ultimately leads to their elimination by the immune system. &nbsp;The current technology uses modified CD4 as a cell surface marker to purify modified stem cells using immunomagnetic beads. This method both protects the marked cells from an immune response and maintains their viability. &nbsp;Reference Number: D-1356&nbsp;Market Applications:&bull;Medical technologies&nbsp;Features, Benefits, &amp; Advantages:&bull;Lack of cytoplasmic tail...]]></description><pubDate>Thu, 11 Oct 2018 08:42:32 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28978</guid></item><item><title>Using glycoside hydrolases to treat biofilm-associated infections</title><caseId>D-1536</caseId><link>http://ttusorc.technologypublisher.com/technology/28756</link><description><![CDATA[Chronic wounds create large healthcare costs and complicate patient healing. Biofilms are a recurring cause of such wounds due to their resilience to antibiotics. Currently, there are no outstanding treatments. The standard of care is debridement followed by antibiotics, however these infections can be hard to treat because of the biofilms. This is in part because the extra polymeric substance (EPS), which is the backbone of biofilms, creates physical and chemical barriers to antibiotics.&nbsp;This technology is a specific combination of enzymes that have the ability to dismantle and degrade t...]]></description><pubDate>Mon, 17 Sep 2018 13:48:01 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28756</guid></item><item><title>Water Soluble Modified Mitochondria Division Inhibitor 1</title><caseId>D-1294</caseId><link>http://ttusorc.technologypublisher.com/technology/28755</link><description><![CDATA[Mitochondrial diseases are broad, they range from metabolic disorders to Huntington's diseases, Alzheimer's diseases, Parkinson's disease and schizophrenia. It is known that excessive mitochondrial division can contribute to apoptosis and therefore mitochondrial division inhibitors are an attractive therapeutic.Mitochondrial division inhibitor 1 (Mdivi-1) is known to inhibit mitochondrial division by blocking dynamin GTPase activity. Mdivi-1 is only soluble in dimethyl sulfoxide, this limits its use in animals and humans.&nbsp;This technology is a modified Mdivi-1 that is soluble in water. The...]]></description><pubDate>Mon, 17 Sep 2018 13:43:43 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28755</guid></item><item><title>Method for creating a synthetic pulse on an actor during medical simulation</title><caseId>D-1293</caseId><link>http://ttusorc.technologypublisher.com/technology/28754</link><description><![CDATA[Medical training and simulation methods have made progress over the years, however, the progress made fails in comparison to other fields. New and improved electronic aids have seen huge improvements for both diagnosis and treatment, but little has been developed in the way of electronic training and simulation devices. &nbsp;The current invention proposes a method that will generate an electronically controlled pulse on a standardized patient actor for medical simulation purposes. The pulse can be varied, and may have both regular and irregular rhythm.&nbsp;Reference Number: D-1293&nbsp;Marke...]]></description><pubDate>Mon, 17 Sep 2018 13:25:45 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28754</guid></item><item><title>Surface modification of Zero Valent Iron Material for Enhanced Reactivity for Degrading Chlorinated Contaminants in Water</title><caseId>D-1239</caseId><link>http://ttusorc.technologypublisher.com/technology/28752</link><description><![CDATA[Environmental remediation in areas contaminated with pollutants typically employ iron-based treatment when cleaning pesticides and heavy metals. In this process the addition of a second metal enhances the reactivity of lead. This is because the metal serves as a catalyst, thus reduction can happen much quicker. The issue is that these metals themselves are pollutants and very sensitive to the environment of the groundwater in which they are added to treat compounds. This means that these catalyzed zero-valent iron-bimetallic nanoparticles are easily deactivated by groundwater solutes.&nbsp;Thi...]]></description><pubDate>Mon, 17 Sep 2018 13:17:48 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28752</guid></item><item><title>method to generate microfractures by chemical reaction in low-carbonate-content shale reservoirs</title><caseId>D-1504</caseId><link>http://ttusorc.technologypublisher.com/technology/28571</link><description><![CDATA[In oil and gas production, many of the easy to access wells have already been drilled. Due to increasing energy demand, new methods that improve hydrocarbon extraction are needed. A common method to crack reservoir rocks is hydraulic fracturing, this involves pumping water, sand and chemicals into the reservoir at high pressures. In turn, this will crack the reservoir rock and provide a channel for oil and gas to flow through.&nbsp;This technology provides an effective method to generate microfractures in a carbonate minerals-bearing shale reservoir. The invention improves hydraulic fracturing...]]></description><pubDate>Mon, 27 Aug 2018 13:59:55 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28571</guid></item><item><title>Label–free, high-throughput holographic screening and enumeration of tumor cells in blood</title><caseId>D-1376</caseId><link>http://ttusorc.technologypublisher.com/technology/28293</link><description><![CDATA[Technology SummaryCirculating tumor cells (CTCs) are cells that have entered the peripheral blood of cancer patients after having left primary or metastatic tumors. Identifying the presence and assessing the characteristics of these CTCs through liquid biopsies has shown great promise for improving cancer patient care by enabling early cancer detection.&nbsp;Current methods of selective CTC identification require coupled labeling with fluorescent markers and antibodies. Although successful, this method is destructive to the sample and requires cumbersome extra steps, preventing further testing...]]></description><pubDate>Wed, 25 Jul 2018 10:04:28 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28293</guid></item><item><title>Modified minocyclines for the treatment and prevention of alcohol use disorder</title><caseId>D-1521</caseId><link>http://ttusorc.technologypublisher.com/technology/28166</link><description><![CDATA[Technology SummaryAlcohol use disorder (AUD) affects millions of people worldwide and lacks a strong pharmaceutical option for treatment. Minocycines have been shown to have great therapeutic potential due to their positive interactions with the central nervous system, their main drawback being unwanted bactericidal effects and toxicity. This technology encompasses a number of modified minocycline compounds and their method of use. These compounds shed their problematic antibiotic effects, yet retain potency against AUD, pain, and other inflammatory conditions.&nbsp;Reference NumberD-1521D-142...]]></description><pubDate>Thu, 19 Jul 2018 12:44:34 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28166</guid></item><item><title>Modified Tetracycline for treatment of disorders involving potential inflammatory processes</title><caseId>D-1429</caseId><link>http://ttusorc.technologypublisher.com/technology/28165</link><description><![CDATA[Technology SummaryAlcohol use disorder (AUD) affects millions of people worldwide and lacks a strong pharmaceutical option for treatment. Minocycines have been shown to have great therapeutic potential due to their positive interactions with the central nervous system, their main drawback being unwanted bactericidal effects. This technology encompasses a number of modified minocycline compounds and their method of use. These compounds shed their problematic antibiotic effects, yet retain potency against AUD, pain, and other inflammatory conditions.&nbsp;Reference NumberD-1521D-1429&nbsp;Market...]]></description><pubDate>Thu, 19 Jul 2018 12:23:52 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28165</guid></item><item><title>Increasing the cell wall and cellulose content in plants by mutating FKF gene and blue light.</title><caseId>D-1509</caseId><link>http://ttusorc.technologypublisher.com/technology/28121</link><description><![CDATA[Technology SummaryBiofuels are an integral part of the ever growing renewable energy landscape. As with any harvesting or manufacturing strategy, yield matters greatly in determining the viability and profitability of the process. This technology is a strategy to increase cellulose and cell wall content in plants, thereby increasing the percent yield of these components for biofuels or other purposes. This is accomplished through a known gene that had not previously been implicated in cellulose or cell wall synthesis in combination with specific light frequency ranges.&nbsp;Reference NumberD-1...]]></description><pubDate>Mon, 16 Jul 2018 13:59:48 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28121</guid></item><item><title>High-throughput fabrication of patterned surfaces and nanostructures by hot-pulling of metallic glass arrays</title><caseId>D-1225</caseId><link>http://ttusorc.technologypublisher.com/technology/28112</link><description><![CDATA[Metallic glasses are emerging engineering materials because of their unique mechanical properties and polymer-like thermoplastic processing. Structures ranging from nano to macro-scale have been fabricated by thermoplastic molding of metallic glasses against templates. However, template-based thermoplastic molding suffers major hurdles such as: shallow features due to increase in processing pressure with increasing aspect-ratio and use of expensive disposable templates. &nbsp;The new technology is a method that manipulates the flow behavior of metallic glasses to either enable complete demoldi...]]></description><pubDate>Fri, 13 Jul 2018 12:19:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28112</guid></item><item><title>Integrated droplet generator using rectified microfluidic pump</title><caseId>D-1188</caseId><link>http://ttusorc.technologypublisher.com/technology/28111</link><description><![CDATA[Droplet generators are excellent tools for generating highly reproducible micro sized droplets with much higher precision and repeatability compared to conventional methods. This technology has been well developed and utilized as a quantitative biomedical research tool. The disclosed technology is a syringe-pump free portable droplet generator designed to generate droplets by on-chip micro-pump array and programmable for different sized droplet generation.&nbsp;Conventional droplet generators require bulky syringe pumps and tubing which results in them being heavy and large in dimension (about...]]></description><pubDate>Fri, 13 Jul 2018 12:17:59 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28111</guid></item><item><title>Development of kanamycin derivatives as connexin hemichannel inhibitors</title><caseId>D-1534</caseId><link>http://ttusorc.technologypublisher.com/technology/28089</link><description><![CDATA[Technology SummaryConnexin hemichannel&rsquo;s play a role in several disorders and diseases, including deafness, cataracts, and ischemic damage of the heart, brain, and kidneys. Aminoglycosides have been shown to inhibit these channels, but their antibiotic effects are problematic. This invention is comprised of several aminoglycoside derivatives that keep their beneficial channel inhibiting properties, but drop their problematic antibiotic effects, making them ideal candidates to be explored for pharmaceutical and therapeutic use.&nbsp;Reference NumberD-1534&nbsp;Market Applications&bull;&nb...]]></description><pubDate>Thu, 12 Jul 2018 08:42:27 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28089</guid></item><item><title>Seamless Mode Change between Grid-connected
Mode and Islanded Mode for PV Systems</title><caseId>D-1488</caseId><link>http://ttusorc.technologypublisher.com/technology/28048</link><description><![CDATA[Technology SummaryDistributed generators, including solar power, in the microgrid, must be able to work in both grid-connected mode and islanded mode (the condition in which a distributed generator continues to power a location even though electrical grid power is no longer present), with good transient performances during mode changes.&nbsp; This technology is a way for photovoltaic (PV) systems to achieve seamless mode changes between the grid-connected mode and islanded mode. This technology overcomes limitations in current systems, which struggle to change modes efficiently and effectively...]]></description><pubDate>Mon, 09 Jul 2018 09:52:44 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28048</guid></item><item><title>A Chemically Functionalized Paper-based Microfluidic Platform for Multiplex Heavy Metal Detection</title><caseId>D-1526</caseId><link>http://ttusorc.technologypublisher.com/technology/28022</link><description>Technology SummaryRecently, there has been a growing interest in the field of paper-based microfluidcs. This technology is being utilized for medical screening, point-of-care (POC) applications, and environmental monitoring. However, most of these devices still require expensive equipment or personnel. The new chemically patterned paper-microfluidic device (cPMD) can be used for a vast range of biomedical and environmental applications. The forces of the paper generate fluid flow without the need for external pumps. This technology allows for diagnostics analysis of various biochemical structu...</description><pubDate>Tue, 03 Jul 2018 08:32:27 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28022</guid></item><item><title>Safe Food Colorant from Sorghum Bicolor Roots</title><caseId>D-1432</caseId><link>http://ttusorc.technologypublisher.com/technology/28010</link><description><![CDATA[A mutation in the Sorghum Bicolor plant causes an increase in the accumulation of 3-deoxyanthocyanin, a pigment molecule, in the plant&rsquo;s roots. This pigment can be easily extracted and used as a natural food colorant. Recent research has shown that artificial and synthetic food colorants, such as yellow 6 and red 40, can have adverse effects on health. While plant metabolites have been used as food dyes for centuries, there has not been a large amount research in the industrial applications of these metabolites as food colorants. Research is continuing to identify the&nbsp; gene or genes...]]></description><pubDate>Mon, 02 Jul 2018 13:22:13 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/28010</guid></item><item><title>New self-attenuated prophylactic and therapeutic vaccines against microbial pathogens such as influenza viruses.</title><caseId>D-1508</caseId><link>http://ttusorc.technologypublisher.com/technology/27913</link><description><![CDATA[Technology SummaryTypically live-attenuated viruses alter the viral genome by deletions or mutations that render the virus inert. This is a live-attenuated vaccine for influenza that incorporates microRNA's into the viral genome to attenuate viral replication. This is shown to be beneficial for several reasons including: a robust immune response, another layer of control to attenuate the virus, efficacy as a therapeutic as well as a vaccine, and cross-strain protection.&nbsp;Reference Number D-1508 Market Applications-vaccines-therapeutics Features, Benefits and Advantages-potent immune respon...]]></description><pubDate>Wed, 20 Jun 2018 12:26:59 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27913</guid></item><item><title>Sensors based on non-covalent complexes.</title><caseId>D-1500</caseId><link>http://ttusorc.technologypublisher.com/technology/27907</link><description><![CDATA[Technology SummarySensors that ascertain the presence of certain anionic or cationic species in an environment are critical to safety, research, medical diagnostics, and quality assurance and control. Regulation of these species in physiological mechanisms (e.g., metabolism, immune response) is necessary to prevent ailments such as cancer or diabetes.&nbsp; Traditionally, users have detected ions through methods such as titration, gas chromatography, and voltammetry.&nbsp; However, these methods have been eclipsed by fluorescence-based sensors, because of their fast responses, high sensitivity...]]></description><pubDate>Wed, 20 Jun 2018 07:51:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27907</guid></item><item><title>Ankle fusion nail - further development</title><caseId>D-1453</caseId><link>http://ttusorc.technologypublisher.com/technology/27854</link><description><![CDATA[Technology SummaryIn orthopedic surgery, nails are frequently used to fuse joints.&nbsp; In orthopedic ankle surgery, there is no nail currently available with the ability to fuse the ankle joint without also fusing the subtalar joint.&nbsp; This results in substantial arch pain for the patient as well as decreased mobility and impaired gait.&nbsp; This technology provides a new type of nail design that can fuse ankle joints without also fusing the subtalar joint while also aiding in compression and stability with strategically placed locking screws.&nbsp; It represents a significant improveme...]]></description><pubDate>Tue, 12 Jun 2018 09:05:45 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27854</guid></item><item><title>Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells</title><caseId>D-1448</caseId><link>http://ttusorc.technologypublisher.com/technology/27835</link><description>Technology SummaryThe use of EGFR inhibitors in the treatment of NSCLC is well established, even being used as a first-line treatment for certain drugs like Gefitinib and Osimertinib. However, eventual drug-resistance by the tumor to these treatments remains a problem. This technology showcases how CRM1 inhibitor Leptomycin B can potentiate the EGFR inhibitor Gefitinib, diminish resistance, and even resensitize tumor cells to Gefitinib. The technology is a method for using CRM1 inhibitors alongside EGFR inhibitors in lung-cancer treatment to mitigate acquired drug resistance, resensitize resis...</description><pubDate>Wed, 06 Jun 2018 11:45:36 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27835</guid></item><item><title> Disulfiram is a Direct and Potent Inhibitor of MGMT in Brain Tumor Cells</title><caseId>D-1000</caseId><link>http://ttusorc.technologypublisher.com/technology/27745</link><description><![CDATA[MGMT is a DNA repair protein that interferes with the cytotoxic action of alkylating chemotherapy agents.&nbsp; Because of the prevalence of this protein in tumors, especially brain tumors, there is a great need for the discovery of an inhibitor that will not harm bone marrow stem cells.&nbsp; This invention has solved this problem through the discovery of a novel use for an existing FDA approved drug used for the treatment of alcoholism, disulfiram.&nbsp;Reference Number: D-1000&nbsp;Market Applications:Cancer Therapeutics&nbsp;Features, Benefits, and Advantages:The alcohol aversion drug disu...]]></description><pubDate>Tue, 22 May 2018 08:13:02 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27745</guid></item><item><title>Always In Reach (AIR) Intubation Tray</title><caseId>D-1363</caseId><link>http://ttusorc.technologypublisher.com/technology/27129</link><description>In modern medicine, an intubation procedure is performed on patients who are unconscious or who cannot breath on their own. An intubation procedure places a tube into the airway of the patient to allow ventilation of the lungs. Whether performed in the Emergency Medicine Department or in a controlled operating room, intubation can carry a significant risk. Emergency Medicine intubations have a 12% adverse event rate. These complications are mainly from inadequate preparation or planning on the part of clinicians. Planning and preparation may be difficult in the emergency department due to sudd...</description><pubDate>Wed, 14 Feb 2018 14:35:47 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27129</guid></item><item><title>Rapid Dissolution of Cotton Cellulose</title><caseId>D-1437</caseId><link>http://ttusorc.technologypublisher.com/technology/27128</link><description><![CDATA[Cellulose is the most abundant, natural, renewable, and biodegradable polymer on earth. Cellulose from cotton has many applications such as, making paper products, making fibers for cloths, and as food additives. For most applications, cotton cellulose must first be dissolved. The structure of cotton and the strong network of hydrogen bonds make cellulose very stable; therefore, making it difficult to dissolve in water based or other common organic solvents. &nbsp;This technology is a new method for the dissolution of cotton cellulose. This method is able to dissolve cotton cellulose in 15 min...]]></description><pubDate>Wed, 14 Feb 2018 14:27:07 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27128</guid></item><item><title>Reduction of pathogens and other bacteria in food products including pet food and rendered products
utilizing a multiple inhibition system with lactic acid bacteria</title><caseId>D-1381</caseId><link>http://ttusorc.technologypublisher.com/technology/27127</link><description><![CDATA[Pets may be asymptomatic carriers of Salmonella, a harmful foodborne pathogen, and consequently, humans may be contaminated through close contact with pet feces. From both a public health and a veterinary viewpoint, controlling Salmonella in pets and their food is of high importance. Consumer education about handling and storing pet food, as well as cleaning up after pets, has been the primary means for combatting Salmonella infections. &nbsp;Pet food that is coated with the products of this technology may prevent the contamination of the food, and in turn, prevent pets from becoming Salmonell...]]></description><pubDate>Wed, 14 Feb 2018 14:18:43 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27127</guid></item><item><title>Wide - injection range Open Circuit Voltage Decay system</title><caseId>D-1353</caseId><link>http://ttusorc.technologypublisher.com/technology/27126</link><description><![CDATA[Today&rsquo;s semiconductors have the drawback of having a voltage hold off and electric current conduction limits. The materials the semiconductors are made of cause this limitation; therefore, newer semiconducting materials (normally WBG semiconductors) with intrinsic material parameters that are better suited for higher voltage and current levels are being tested. One of the many tests being performed is material parameter extraction and the disclosed invention is a new system to accomplish this. &nbsp;This technology is a single piece of equipment that performs a wide injection range OCVD ...]]></description><pubDate>Wed, 14 Feb 2018 14:12:07 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27126</guid></item><item><title>Anticancer effects of Pimavanserin, a known anti-Parkinson drug</title><caseId>D-1409</caseId><link>http://ttusorc.technologypublisher.com/technology/27125</link><description><![CDATA[Cancer treatment methods must meet rigorous constraints before being approved by the FDA for administration to patients. Consequently, it is estimated that in 2012, more than 50% of the diagnosed cancer cases died worldwide due to these constraints preventing usage and treatment. It is becoming increasingly important to present more options for cancer treatment, and improve on existing methods to increase the likelihood of FDA acceptance. &nbsp;Taking advantage of an FDA-approved substance, this technology led to 75% suppression in tumor growth in an orthotopic pancreatic cancer model. Pending...]]></description><pubDate>Wed, 14 Feb 2018 14:03:41 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27125</guid></item><item><title>Utilizing the complete Fibrogram for fiber quality evaluation</title><caseId>D-1445</caseId><link>http://ttusorc.technologypublisher.com/technology/27123</link><description><![CDATA[In the textile industry, there are different types of machines that are able to assess the quality of fibers, with the most common being the high volume instrument (HVI). HVI systems take parallel bundles of fibers and report on the mean length and uniformity index of the bundle. However, there is very little data reported concerning individual fiber metrics of the distribution of fiber lengths. Without these added fiber qualities, the ability to accurately predict yarn quality becomes much harder.&nbsp; One way around this lack of information is to use a different method of fiber analysis kno...]]></description><pubDate>Wed, 14 Feb 2018 13:30:45 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27123</guid></item><item><title>A device and technique to allow high resolution delineation of contaminant concentrations, biogeochemical processes, and microbial communities in saturated subsurface environments</title><caseId>D-1271</caseId><link>http://ttusorc.technologypublisher.com/technology/27122</link><description>Over the years, numerous technologies and prediction models have been developed to both predict where and how fast the subsurface contamination will move and how it might affect groundwater. However, all of these technologies are contingent on understanding the location of the contaminants, how much contamination is present, and what processes are affecting the contaminants. This information can be often very difficult to obtain, as the subsurface is often very complex, consisting of numerous types and variable depths of soils. Traditionally, drilling wells and groundwater testing have primari...</description><pubDate>Wed, 14 Feb 2018 12:38:15 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27122</guid></item><item><title>Rapid Analysis of Metal-laden Water via Portable X-ray Fluorescence Spectrometry.</title><caseId>D-1444</caseId><link>http://ttusorc.technologypublisher.com/technology/27121</link><description>Water salinity is vital to environmental quality assurance, environmental health, and human health. Soil and water salinity are naturally linked on slurries or saturated pastes whereby salts precipitated in soil dissolve into solution. Currently, this type of salinity analysis is conducted by using electrical conductance. Salts in soil and water are normally not detectable without laboratory analysis. Therefore, there is a need for a more convenient and better way to test water for these salt elements. Recently, portable X-ray Fluorescence (PXRF) spectrometry had rapidly developed so that test...</description><pubDate>Wed, 14 Feb 2018 12:31:15 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27121</guid></item><item><title>Pollen grains for treatment of peanut and other allergies</title><caseId>D-1374</caseId><link>http://ttusorc.technologypublisher.com/technology/27120</link><description>Peanut allergy is a life-threatening condition that affects approximately 3 million people in the United States. It is typically diagnosed early in life, and only 20% of children outgrow their allergy. Currently, there are no FDA approved methods of treatment, so those affected must avoid peanut products entirely and carry an epinephrine injection in case of an allergic reaction to prevent anaphylaxis. Peanut oral immunotherapy aims to treat peanut allergy by modulating the immune response through escalating the dosage of peanut protein over time, starting with the smallest dose, and steadily ...</description><pubDate>Wed, 14 Feb 2018 12:22:34 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27120</guid></item><item><title>Rod pump gas separation in horizontal oil wells</title><caseId>D-1369</caseId><link>http://ttusorc.technologypublisher.com/technology/27119</link><description><![CDATA[Horizontal wells that utilize rod pumps often use a gas separator to remove gaseous content from oil prior to pumping. These systems require complicated downhole configurations and expensive packing materials. This technology provides a simplistic alternative to gas separators that may simultaneously reduce both gas interference and oil well completion costs.&nbsp; The well will be able to effectively pump out just oil, reducing mechanical failures that occur when gaseous content is introduced to the pump. This will also lower the intake pressure at the perfections to result in a lower measure...]]></description><pubDate>Wed, 14 Feb 2018 12:14:55 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27119</guid></item><item><title>Polymer nanodiscs for biotechnology and medical applications</title><caseId>D-1303</caseId><link>http://ttusorc.technologypublisher.com/technology/27118</link><description><![CDATA[Membrane proteins (MP) mediate many of the cell&rsquo;s fundamental processes and MPs are embedded in the cell&rsquo;s membrane lipid bilayer. Currently, MPs are targets for about 60% of therapeutic drugs in use. &nbsp;However, MPs are very difficult to manipulate and study because they require both an aqueous environment and need transmembrane hydrophobic regions. Because this is tricky and difficult to achieve, most studies use the protein solubilized in detergent. Because of this particular setup, these study systems have limited stability. &nbsp;To address this, the industry has used lipos...]]></description><pubDate>Wed, 14 Feb 2018 12:07:19 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27118</guid></item><item><title>Zwitterionic Styrene–Maleic Amide Copolymers for the Preparation of Lipid and Polymer Membrane
Nanodiscs</title><caseId>D-1387</caseId><link>http://ttusorc.technologypublisher.com/technology/27117</link><description><![CDATA[Membrane proteins (MP) mediate many of the cell&rsquo;s fundamental processes and MPs are embedded in the cell&rsquo;s membrane lipid bilayer. Currently, MPs are targets for about 60% of therapeutic drugs in use. However, MPs are very difficult to manipulate and study because they require both an aqueous environment and need transmembrane hydrophobic regions. Because this is tricky and difficult to achieve, most studies use the protein solubilized in detergent. Because of this particular setup, these study systems have limited stability. &nbsp;This technology comprises three different syntheti...]]></description><pubDate>Wed, 14 Feb 2018 09:38:45 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27117</guid></item><item><title>Chemical probes with anti-inflammatory, neuroprotective and anticancer properties</title><caseId>D-1428</caseId><link>http://ttusorc.technologypublisher.com/technology/27115</link><description><![CDATA[Many diseases and disorders of the brain cause swelling of brain tissue also known as neuroinflammation. Neuroinflammation is beginning to be recognized as one of the hallmark signs and disease progression factors of Alzheimer&rsquo;s and Parkinson&rsquo;s disease. The swelling of brain tissue can limit the amount of blood flow to areas in the brain and can inhibit the body&rsquo;s natural disease fighting mechanisms. Traumatic brain injuries (TBI) also cause significant neuroinflammation. Unresolved and severe brain edema is the leading cause of death for TBI patients within the first few day...]]></description><pubDate>Wed, 14 Feb 2018 09:21:16 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27115</guid></item><item><title> Low Cost Method to Measure Fluid Properties of Viscoelastic Fluids</title><caseId>D-1037</caseId><link>http://ttusorc.technologypublisher.com/technology/27114</link><description><![CDATA[Fluid mechanics enable the accurate and analytical characterization of complex fluids, their flow, and their properties. However, many of the measurement techniques utilized to measure the frequency-dependent coefficients of viscoelastic fluids involve the use of expensive measurement devices and time-consuming experimental set-ups.&nbsp; This technology proposes an inexpensive and relatively swift procedure whereby the necessary fluid properties (frequency-dependent coefficients) of complex, viscoelastic fluids can be determined. &nbsp;Reference Number: D-1037&nbsp;Market Applications:The tec...]]></description><pubDate>Wed, 14 Feb 2018 09:10:40 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/27114</guid></item><item><title>Tunable nanocomplexes for delivery of plasmid DNA into human and vertebrate primary cells</title><caseId>D-1451</caseId><link>http://ttusorc.technologypublisher.com/technology/26939</link><description><![CDATA[Historically, poly(D,L-lactide-co-plycolide) (PLGA) complexes with polyethylenimine (PEI) coated surfaces have been used&nbsp; as a DNA delivery mechanism in gene therapy. This allows for a complex that has relatively low cytotoxicity, binds DNA, and has a cationic surface to allow for easy entry into the target cell. However, these complexes still maintain an amount of cytotoxicity due to the nature of PEI. Smaller PEI molecules have low cytotoxic effects, but then have almost no transfection ability. The present invention uses lower molecular weight PEI along with an attached glycidyl hexade...]]></description><pubDate>Mon, 22 Jan 2018 09:55:53 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/26939</guid></item><item><title>A No Suture Chest Tube</title><caseId>D-1389</caseId><link>http://ttusorc.technologypublisher.com/technology/26938</link><description>In Emergency and Trauma Medicine, chest tubes are common medical devices used to treat patients. Typically, chest tubes are used to treat pneumothorax, air around the lung, and hemothorax, blood or fluid around the lung, in a trauma situation; however, they also can be used to treat other spontaneous conditions such as cancer, COPD, or body habitus. Current practices for a patient requiring a chest tube would be to make a skin incision across the rib, insert the chest tube, and then use sutures to secure the tube within the chest and allow for the fluid to drain. Dressing for a typical chest t...</description><pubDate>Mon, 22 Jan 2018 08:31:12 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/26938</guid></item><item><title>Development of Virus like particle (VLP) vaccine and reporter assay for ZIKA virus</title><caseId>D-1406</caseId><link>http://ttusorc.technologypublisher.com/technology/26124</link><description><![CDATA[The Zika virus outbreaks throughout the world have prompted an immediate need for a vaccine.&nbsp; Currently, there is not an approved vaccine to treat Zika and application of DNA based vaccines has posed severe risks, such as insertional mutagenesis.&nbsp; Due to these threats, the FDA is unlikely to approve DNA based vaccines.&nbsp;This invention has identified a method of creating a vaccine for the Zika virus, which is not DNA based, providing a safer and more effective treatment approach.&nbsp; The research has identified a mechanism of modifying the Zika virus to create VLPs that are capa...]]></description><pubDate>Fri, 01 Sep 2017 13:21:01 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/26124</guid></item><item><title>Highly Selective AKR1C3 Inhibitors and Methods of Use Thereof</title><caseId>D-1318</caseId><link>http://ttusorc.technologypublisher.com/technology/26122</link><description><![CDATA[The enzyme, aldo-keto reductase family 1-member C (AKR1C3), is a well-known contributor to prostate cancer, acute myeloid leukemia, and chemotherapeutic resistance.&nbsp; However, current inhibition research has only identified compounds with an insufficient degree of selectivity for AKR1C3 over its other isoforms.&nbsp;This invention has established a method of synthesizing an AKR1C3 inhibitor with 1800 fold selectivity over related isoforms and permits more effective cancer treatment.&nbsp; The research has identified known AKR1C3 inhibitors and altered them to increase selectivity.&nbsp; Un...]]></description><pubDate>Fri, 01 Sep 2017 12:26:25 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/26122</guid></item><item><title>Method and Apparatus for Gender Selection Based on PH</title><caseId>D-0560</caseId><link>http://ttusorc.technologypublisher.com/technology/26063</link><description><![CDATA[The present invention includes methods and apparatus to numerically enhance semen populations with cells of one sex as to increase the chances of having an offspring of the desired sex.&nbsp; Sperm cells in a populations are exposed to different pH values and the exposure allows mobile sperm cells to migrate to different pH environments.&nbsp; Theses cell are then collected according to their X or Y chromosome characteristics and used in artificial insemination to influence the sex of the offspring.&nbsp; &nbsp; &nbsp;Reference Number:&nbsp; D-0560&nbsp;Features, Benefits &amp; Advantages:Impr...]]></description><pubDate>Fri, 18 Aug 2017 14:55:54 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/26063</guid></item><item><title>V2 Pharmacoperone</title><caseId>D-1209</caseId><link>http://ttusorc.technologypublisher.com/technology/23899</link><description><![CDATA[This invention reports pharmacoperones for their novel use of therapeutics in the treatment of nephrogenic diabetes insipidus (NDI). Pharmacoperones are small molecules that enter the cell and serve as a scaffolding to allow mutated proteins to route correctly. In NDI, there is a mutation in the V2 receptor protein. Here, the inventor has reported over 140 pharmacoperones to the V2 receptor; therefore, the pharmacoperones may act as drugs specifically against the known pathology of NDI.&nbsp;Reference Number: D-1209&nbsp;Market Applications:&nbsp;Pharmaceutical Industry&nbsp;Features, Benefits...]]></description><pubDate>Mon, 30 Jan 2017 15:04:59 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23899</guid></item><item><title>Optimum Design for Gas Lift Valve Seat</title><caseId>D-1308</caseId><link>http://ttusorc.technologypublisher.com/technology/23897</link><description><![CDATA[This invention reports an optimization to the principle of gas lift to increase oil production using a gas lift system. Gas lift is an artificial lift that uses external sources of high-pressure gas to supplement formation gas in order to lift the well fluid. This invention reports the optimum design as reducing the amount of stem travel required to generate flow area equivalent to the port area. Further, the reported design addresses the issue of bellows efficiency and can circumvent the lack of it in current systems' gas lift valve performance.&nbsp;Reference Number: D-1308&nbsp;Market Appli...]]></description><pubDate>Mon, 30 Jan 2017 13:45:34 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23897</guid></item><item><title>A novel method for producing hollow exine shells from pollen grains</title><caseId>D-1335</caseId><link>http://ttusorc.technologypublisher.com/technology/23889</link><description>Pollen grains are naturally occurring microcapsules produced by plants. Hollow pollen shells have been found useful for pharmaceutical drug delivery among other uses. To be of use for these purposes, pollen shells must be emptied of their proteinaceous material. The conventional method uses an organic solvent to defatten the pollens, then applies an alkali treatment to remove the proteinaceous material from the inside of the pollen, and ends with an acid treatment to remove the intine, which is the inner layer of the pollen shell. This method is often used on Lucopodium clavatum spores to prod...</description><pubDate>Fri, 27 Jan 2017 12:29:46 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23889</guid></item><item><title>Toddler Mobility Device</title><caseId>D-1349</caseId><link>http://ttusorc.technologypublisher.com/technology/23888</link><description><![CDATA[For parents of children with disabilities, extremely expensive power chairs may be purchased for children above the age of five. These chairs are generally tall, bulky, and difficult to transport. But for parents of disabled children below the age of five, there are no options on the market for chairs that will allow the child freedom to move, or means to develop cognitive spatial awareness, which is crucial between the ages three to five.&nbsp;This technology is a mobility device that provides children with disabilities under five years the means to achieve self initiated mobility. With a lig...]]></description><pubDate>Fri, 27 Jan 2017 12:20:57 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23888</guid></item><item><title>Pharmacophore elucidatin of phosphodynine A - Potent and selective Peroxisome Prolferator-Activated Receptor  agonists with neuroprotective activity</title><caseId>D-1262</caseId><link>http://ttusorc.technologypublisher.com/technology/23869</link><description>Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors and ligand-activated transcription factors that play significant roles in cellular processes. Some isoforms have been validated as therapeutic targets in certain diseases. The role of isoform PPARdelta has not yet been fully explored due to its ubiquitous expression. However, with recent identification of selective chemical probes specific to PPARdelta, this receptor/transcription factor may emerge as a potentially promising pharmacological target for the treatment of a range of neurodegenerative dise...</description><pubDate>Tue, 24 Jan 2017 14:46:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23869</guid></item><item><title>ROXI: An electronic lab solution</title><caseId>D-1259</caseId><link>http://ttusorc.technologypublisher.com/technology/23851</link><description><![CDATA[A laboratory is a room equipped to conduct scientific experiments, test, investigations, or to manufactures compounds like chemicals or pharmaceuticals. Laboratories are an essential part of science-based curriculum, however, they are a resource largely unavailable to to online students. As enrollment in online classes is increasing, science courses must be adaptable to meet the needs of the online student.&nbsp;This technology is a device outfitted with a variety of sensors common to measurement-based physical science courses. The software uses a computer USB connection to guide the learner t...]]></description><pubDate>Mon, 23 Jan 2017 14:44:57 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23851</guid></item><item><title>Soluble chimeras of the intracellular domain of pentameric ligand-gated ion channels</title><caseId>D-1275</caseId><link>http://ttusorc.technologypublisher.com/technology/23845</link><description>Pentameric ligand-gated ion channels (pLGICs) of the Cys-loop superfamily are receptors for neurotransmitters such as glycine, glutamate, nicotinic acetylcholine, and serotonin. These receptors are the targets for a number of currently used clinical drugs, including general anesthetics, anti-epileptics (anto-convulsants), sedatives, anxiolytics, and muscle relaxants. Understanding how each of these receptors function and identifying/characterizing the different structural elements that mediate each aspect of their function is imperative for developing new and better drugs as well as improving ...</description><pubDate>Fri, 20 Jan 2017 14:01:51 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23845</guid></item><item><title>RAIDR– A Rapid Method for the Microextraction of O-Glycans</title><caseId>D-1341</caseId><link>http://ttusorc.technologypublisher.com/technology/23792</link><description><![CDATA[O-glycosylation, a common post-translational modification of serine and threonine residues, regulates biological processes through the direct interactions of glycans with binding proteins. O-glycosylation modulates protein stability, conformation, solubility, and lifespan; however, it has also been implicated in the pathogenesis of a number of diseases, which has stimulated interest in analytical methods capable of isolating O-glycans for further characterization. &nbsp;The technology is a method termed Rapid Ammonium hydroxide Isobutyric acid O-glycan Deglycosylation Reaction (RAIDR) for the ...]]></description><pubDate>Tue, 10 Jan 2017 15:00:37 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23792</guid></item><item><title>3D PRINTING COTTON CELLULOSE BASED CONDUCTIVE COMPOSITES</title><caseId>D-1166</caseId><link>http://ttusorc.technologypublisher.com/technology/23617</link><description>In 3D printing, the currently used microcrystalline cellulose (MCC) and cellulose nanocrystals (CNC) have much lower molecular weights and lower degrees of polymerization than raw cotton-based cellulose, which is why they are much easier to dissolve. This technology provides a potentially novel method to produce raw cotton cellulose based conductive materials with the use of (1) a specific freeze-drying pretreatment methodology to increase viscosity and allow homogeneity to meet 3D printing cellulose standards and (2) a 3D printing layer-by-layer technique to incorporate conductive properties....</description><pubDate>Tue, 06 Dec 2016 13:15:01 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/23617</guid></item><item><title>Solid State Smart Transformer</title><caseId>D-1009</caseId><link>http://ttusorc.technologypublisher.com/technology/20829</link><description><![CDATA[Electric transformers generally increase and decrease the voltage of the transmitted electricity appropriately to optimally transmit electricity with minimal power losses. They are used numerously by the utility industry for the transmission of electricity. However, in their present state, the regular transformers perform only the job of voltage escalation or reduction. They do not allow for the collection of electric data at the respective transformer&rsquo;s location in the grid, nor do they communicate with the grid in any way. With the arrival of the smart grid and smart electric devices, ...]]></description><pubDate>Tue, 10 Nov 2015 13:35:57 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20829</guid></item><item><title>Economic Analysis of Renewable and Battery Storage Systems</title><caseId>D-1235</caseId><link>http://ttusorc.technologypublisher.com/technology/20827</link><description><![CDATA[In the past several years, there has been tremendous increase in power production by renewable energy resources and the energy projection profiles indicate that the trend will continue for the next decade. The development and application of battery energy storage systems in various fields such as electric vehicle, renewable energy, and grid has been increasing but the benefits are hard to quantify due to its complexity in different applications.&nbsp; New energy storage technologies could greatly increase the role of renewables, but an economic analysis is essential to understand the feasibili...]]></description><pubDate>Tue, 10 Nov 2015 12:55:02 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20827</guid></item><item><title>Method and model for accurate and fast power flow analysis in power systems operation and planning</title><caseId>D-1236</caseId><link>http://ttusorc.technologypublisher.com/technology/20821</link><description>Power flow analysis in power systems and planning is used to calculate voltage magnitude and angles across power grids. It gives information regarding how power generation and demand is balanced in a system and if there is any excess in demand or shortage in generation that needs to be taken care of. Other applications include but not limited to electricity nodal pricing, unit commitment, expansion planning, contingency analysis, and congestion management. Current power flow analysis is categorized to AC and DC power flow methods. AC power flow has better accuracy compared to DC, however, it i...</description><pubDate>Tue, 10 Nov 2015 09:34:53 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20821</guid></item><item><title>NOVOPLATE: Pipette-integrated droplet-based nanoliter-volume well plate for bioassays</title><caseId>D-1195</caseId><link>http://ttusorc.technologypublisher.com/technology/20820</link><description><![CDATA[With the expansive growth of drug screening and other biological assays, there is a need for technologies that can screen drugs using minimal amounts of the compound volumes.&nbsp; Currently, most multi-well plates and pipetting systems are ubiquitously used for this purpose, but are difficult to scale down for use at the nano-level due to problems of volume evaporation and pipetting errors.&nbsp; Although drop-based microfluidics has recently emerged and show great potential, these technologies are not configured to conduct cell-based drug assays with the same ease and fluid handling capabili...]]></description><pubDate>Tue, 10 Nov 2015 09:18:48 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20820</guid></item><item><title>Post Exposure Vaccination for Anthrax using siRNA</title><caseId>D-1184</caseId><link>http://ttusorc.technologypublisher.com/technology/20671</link><description><![CDATA[Anthrax is a disease that rarely occurs naturally in humans, making it more realistic to develop a post exposure prophylaxis or therapy instead of a program of mass immunization.&nbsp; When the bacteria Bacillus anthracis is introduced into the body, it will later produce the anthrax toxin which affects certain receptors on the host&rsquo;s cells, potentially leading to the host&rsquo;s death. &nbsp;The proposed invention is an engineered anthrax toxin molecule that is not itself toxic. The engineered molecule specifically targets the same receptors that anthrax targets, delivers molecular car...]]></description><pubDate>Thu, 29 Oct 2015 12:19:55 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20671</guid></item><item><title>A Method to Introduce Salmonella into Ground Meat and Poultry for Testing Mitigation Efforts</title><caseId>D-1121</caseId><link>http://ttusorc.technologypublisher.com/technology/20658</link><description><![CDATA[Illnesses related to foodborne pathogens pose a considerable economic strain on the United States annually.&nbsp; Among them, Salmonella enterica is responsible an estimated 1 million yearly cases of foodborne illness. Research has shown that the transfer of Salmonella from the initial animal to consumer meats occurs primarily when peripheral lymph nodes harboring Salmonella are ground into harvested meats at slaughter houses. &nbsp;The disclosed technology utilizes a previously filed technology (US 20140248605 A1) as part of its method to consistently and routinely introduce Salmonella into g...]]></description><pubDate>Tue, 27 Oct 2015 14:15:18 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20658</guid></item><item><title>Computerized Method to Optimize the Calculation of Sigma Profiles</title><caseId>D-1089</caseId><link>http://ttusorc.technologypublisher.com/technology/20644</link><description><![CDATA[The invention is an optimization model used to generate sigma profiles of any concerned molecule from conceptual segment numbers of the molecule and linear combination of sigma profiles of four reference solvents representing hydrophobic, polar attractive, polar repulsive, and hydrophilic conceptual segments. &nbsp;Reference Number: D-1089&nbsp;Market Applications:&bull;&nbsp;Chemical Processing&bull; Product Development&bull; Molecular Diagnostics&nbsp;Features, Benefits, and Advantages:&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This technology allows sigma profiles to be generated or op...]]></description><pubDate>Mon, 26 Oct 2015 15:54:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20644</guid></item><item><title>Biomarkers to Identify  Specific Serotypes of  Salmonella in Real-time</title><caseId>D-1113</caseId><link>http://ttusorc.technologypublisher.com/technology/20640</link><description><![CDATA[Various Salmonella strains are common food born microbes that cause disease in humans and animals. Some strains can cause intestinal infections, while others cause typhoid fever. Because of the large variety of Salmonella strains present and the different pathogenic effects of these strains, it is important to develop rapid and flexible assays that have the capacity to distinguish between these strains. Presently, Salmonella serotype determination takes several days to process and can be inaccurate. &nbsp;A previous technology created by this same research group allows for the rapid detection ...]]></description><pubDate>Mon, 26 Oct 2015 12:17:40 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20640</guid></item><item><title>Touch Free Operation  for Smartphones and Other Handheld Devices</title><caseId>D-1126</caseId><link>http://ttusorc.technologypublisher.com/technology/20615</link><description><![CDATA[Touchscreens are appearing in more and more products and used for controlling the operation of the devices.&nbsp; This is especially true as it relates to smartphones.&nbsp; There is currently no method for the operation of smartphones without some form of physical contact with the phone. Since wireless charging is now a standard feature for many smart phones, a system that leverages the wireless charging coil, can also enable a sensing system that will allow for touch free operation of the device. &nbsp;Smartphone technology utilizes resonant frequency from the wireless power transfer (WPT) c...]]></description><pubDate>Fri, 23 Oct 2015 14:41:18 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20615</guid></item><item><title>FDA approved Parkinson's Therapeutic Found Effectiive in Treatment of Cancer</title><caseId>D-1152</caseId><link>http://ttusorc.technologypublisher.com/technology/20611</link><description><![CDATA[Carbidopa is an FDA approved drug currently used in combination with Levo-Dopa to treat Parkinson&rsquo;s disease.&nbsp; Carbidopa, itself, has no effect on Parkinson's patients, but by increasing the availability of Levo-dopa in the brain enhances the effectiveness of the drug in patients.&nbsp; As such, these two drugs are always prescribed together. &nbsp;Researchers have found that Carbidopa, taken alone, is an effective anticancer drug for the treatment of pancreatic and breast cancer in mouse models.&nbsp; The mechanism of action for Carbidopa is related to the inhibition of a critical i...]]></description><pubDate>Fri, 23 Oct 2015 12:46:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20611</guid></item><item><title>Development of a Phenotypic High-Content Assay to Identify Pharmacoperone Drugs for the Treatment of Primary Hyperoxaluria Type 1 by High-Throughput Screening</title><caseId>D-1154</caseId><link>http://ttusorc.technologypublisher.com/technology/20590</link><description><![CDATA[Hyperoxalosis is a deadly disease for which the best current therapy is dialysis or organ transplant.&nbsp; The underlying cause of some forms of the disease is the misrouting of a specific enzyme; alanine:glyoxylate aminotransferase (AGT) to the mitochondira inststead of the peroxisome.&nbsp; Pharmacoperones are small molecules that can restore proper function to the peroxisome to restore organ function and potentially cure the disease.&nbsp;The discovery of target-specific pharmacoperones by high throughput screening (HTS) requires the design of automation-friendly, microtiter plate-compatib...]]></description><pubDate>Fri, 23 Oct 2015 10:02:12 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20590</guid></item><item><title>Repurposed use of a currently available antibiotic and analogs to reduce alcohol consumption and negative alcohol-related consequences.</title><caseId>D-1164</caseId><link>http://ttusorc.technologypublisher.com/technology/20582</link><description><![CDATA[The U.S. market for substance abuse treatment and diagnosis exceeds $3.1 billion annually, yet no effective drug treatment for alcoholism has been discovered that significantly reduces alcohol consumption. &nbsp;Researchers have re-purposed the use of an FDA approved antibiotic currently available in the market that significantly reduces alcohol consumption in patients. The results of a mouse model study show a statistically significant reduction in alcohol consumption for groups treated with the described drug, with greater percent reductions expressed in males as compared to female subjects....]]></description><pubDate>Thu, 22 Oct 2015 13:37:16 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20582</guid></item><item><title>Drug Combinations to Overcome Resistance to BRAF and MEK Inhibitors</title><caseId>D-1172</caseId><link>http://ttusorc.technologypublisher.com/technology/20581</link><description><![CDATA[The drug Vemurafenib is one of the few treatment options for late-stage melanoma currently available. However, upon either single or chronic treatment with Vemurafenib, the cancer cells develop mechanisms of resistance to the drug.&nbsp; Other drugs available in the market such as Mek1/2 inhibitors and BRAF inhibitors fail to overcome Vemurafenib resistance. &nbsp;This invention has identified the mechanism that creates the resistance to Vemurafenib for the treatment of melanoma, and the class of drugs that are used in combination with Vemurafenib will prevent resistance.&nbsp; The research ha...]]></description><pubDate>Thu, 22 Oct 2015 13:18:40 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20581</guid></item><item><title>Predictive Model for Densities of Aqueous Electrolyte Solutions</title><caseId>D-1244</caseId><link>http://ttusorc.technologypublisher.com/technology/20578</link><description><![CDATA[In most chemical and petroleum industries, the density of aqueous electrolyte solutions is useful in the design and control of chemical processes. It is used in pipe sizing, pump calculations, heat transfer calculations, and other common problems. While standardized values for the densities of many substances are readily available, there are many industrial operations, such as hydraulic fracturing, that produce side products with unknown densities. Hence, the development of a method to calculate the densities of unknown products is very important to chemical manufacturing companies. &nbsp;The ...]]></description><pubDate>Wed, 21 Oct 2015 14:41:32 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20578</guid></item><item><title>Formulations (oral and topical cream) containing anti-cancer agents to prevent or treat melanoma</title><caseId>D-1052</caseId><link>http://ttusorc.technologypublisher.com/technology/20455</link><description><![CDATA[Melanoma is the most serious type of skin cancer and develops in the cells that produce melanin.&nbsp; Treatment for early-stage melanomas usually include surgery to remove the melanoma.&nbsp; If the melanoma has spread beyond the skin, treatment options may include surgery to remove affected lymph nodes and chemotherapy.&nbsp; &nbsp;An effective new drug delivery system has been discovered for oral and topical administration of a promising anti-cancer agent for the treatment of melanoma.&nbsp; A self-emulsifying nanoemulsion system was developed for oral delivery that has resulted in entrapme...]]></description><pubDate>Tue, 06 Oct 2015 15:07:06 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/20455</guid></item><item><title>Method to Design Multiplexed MicroRNA-based shRNA</title><caseId>KoBio, LLC</caseId><link>http://ttusorc.technologypublisher.com/technology/19862</link><description><![CDATA[Previous research has shown that short hairpin RNAs (shRNAs) can be used to inhibit HIV-1 replication.&nbsp; Because HIV-1 evolves very quickly the rapid emergence of escape mutations is a problem.&nbsp; In order to combat this, researchers have begun to use micro RNA (miRNA) backbones to express multiple shRNAs. However, the number of shRNAs that can currently be expressed is limited. This technology has overcome the previous limitations and created a way to express seven or more shRNAs.&nbsp; This method uses minimal flanking sequences, and results in expression that is not decreased with di...]]></description><pubDate>Mon, 29 Jun 2015 09:27:52 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/19862</guid></item><item><title>New live attenuated viral vaccine created by self-attenuation with species-specific artificial microRNA</title><caseId>D-1093</caseId><link>http://ttusorc.technologypublisher.com/technology/19856</link><description><![CDATA[The technology proposes a solution to the potential risks of the current Live Attenuated Influenza Vaccines (LAIV) by proposing a new mammalian-specific LAIV. This was done through the creation of a genetically-engineered influenza virus, that produces an immune response only in mammals.&nbsp; This attenuated vaccine produces mature and functional artificial microRNA.&nbsp; The miRNA specifically targets and successfully silences the influenza NP gene. This potent immune response has also been experimentally shown to provide heterologous protection, or cross-protection, for other strains of th...]]></description><pubDate>Thu, 25 Jun 2015 14:27:27 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/19856</guid></item><item><title>Chemically patterned paper-microfluidic device (cPMD) for medical screening and environmental monitoring</title><caseId>D-1136</caseId><link>http://ttusorc.technologypublisher.com/technology/19855</link><description><![CDATA[This technology allows for diagnostics analysis of various biochemical structures including 2D and 3D networks via a chemical patterning technique without the use of expensive machinery, or the limitations of high temperatures.&nbsp; Additionally, this new method involves coating the paper to create localized hydrophobic and hydrophilic regions.&nbsp; The technique has been validated by various successful patterns and bioassays.&nbsp;Reference Number: D-1136&nbsp;Market Applications:Biomedical Screening of DiseasesEnvironmental Monitoring (i.e. toxic metals in drinking water)&nbsp;Features, Be...]]></description><pubDate>Thu, 25 Jun 2015 14:19:46 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/19855</guid></item><item><title>Ankle (tibio-talar) fusion nail</title><caseId>D-1176</caseId><link>http://ttusorc.technologypublisher.com/technology/19854</link><description><![CDATA[In orthopedic surgery, nails are frequently used to fuse joints.&nbsp; In orthopedic ankle surgery, there is no nail currently available with the ability to fuse the ankle joint without also fusing the subtalar joint.&nbsp; This results in substantial and permanent arch pain for the patient.&nbsp; This technology provides a new type of nail design that can fuse ankle joints without also fusing the subtalar joint.&nbsp; It represents a significant improvement in the results from this type of surgery. &nbsp;Reference Number: D-1176&nbsp;Market Applications:OrthopedicsSurgical InterventionsHealth...]]></description><pubDate>Thu, 25 Jun 2015 14:09:31 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/19854</guid></item><item><title>A biocompatible particle to detect and confirm molecules reactive against the peptide/HLA complex and HLA class I/II molecules</title><caseId>D-1086</caseId><link>http://ttusorc.technologypublisher.com/technology/19853</link><description><![CDATA[The human leukocyte antigen (HLA) is composed of class I and II complexes, which are expressed by nucleated cells in the body. The HLA class system uses specific peptides in order to inform the immune system of the cell's health status. In the case of an abnormal event (e.g., cancer), immunologically-related molecules such as antibodies or lymphocytes bind their cognate HLA-derived peptide and induce the death of the cell through a number of possible effector mechanisms in order to maintain the integrity of the host.&nbsp; &nbsp;This technology consists of a polylactic-co-glycolic acid particl...]]></description><pubDate>Thu, 25 Jun 2015 13:57:51 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/19853</guid></item><item><title>AtRAVs Make Longer Cotton Fibers Under Drought</title><caseId>D-1081</caseId><link>http://ttusorc.technologypublisher.com/technology/18964</link><description><![CDATA[In many countries cotton (Gossypium spp.) is one of the most important fiber producing plants.&nbsp; The main concerns in growing cotton are the inverse relationship between cotton fiber qualities and high yields. The disclosed technology proposes a way to solve the problem of growing immature and short cotton fibers caused by drought stress. There currently are no known solutions to this problem, other than traditional breeding with the modification of particular genes involved in cotton maturation. The technology shows that RAV genes are indeed important for plant hormone abscisic acid and e...]]></description><pubDate>Fri, 24 Apr 2015 07:16:06 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/18964</guid></item><item><title>Computational Tool for Simulation and Design of Discrete Droplet Microfluidic Systems</title><caseId>D-0915</caseId><link>http://ttusorc.technologypublisher.com/technology/17939</link><description><![CDATA[Discrete droplet microfluidic systems are a rapidly expanding technology with applications in many scientific and engineering endeavors that require biochemical analysis.&nbsp; Success in this area depends on developing engineering devices that have precise and multiple functionalities, such as spatial and temporal control of the droplets.&nbsp; This technology is a computerized method for designing discrete droplet microfluidic systems for the simulation and design of these complex microfluidic networks.&nbsp; This design tool provides a modeling platform using nodal analysis and a generic al...]]></description><pubDate>Thu, 15 Jan 2015 14:46:43 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17939</guid></item><item><title>Facilities Space Planning and  Management System</title><caseId>D-0921</caseId><link>http://ttusorc.technologypublisher.com/technology/17452</link><description><![CDATA[This web-based software greatly reduces data entry and management time, and increases the ability to analyze space usage while maintaining 100% accuracy. This database is designed to log all edits or changes, and maximize foreign key constraints. The key features include the ability to edit multiple pieces of information at a single time, ability to execute a mass update, and attachment of multiple sections of information to an entry (i.e. occupants, photos, documents). &nbsp;Reference Number: D-921&nbsp;Market Applications:Software/GIS companiesEducation SystemsHealth InstitutionsHotel Manage...]]></description><pubDate>Fri, 31 Oct 2014 10:44:42 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17452</guid></item><item><title>Matador or HES 1205 Plant Variety Protection</title><caseId>D-0473</caseId><link>http://ttusorc.technologypublisher.com/technology/17449</link><description><![CDATA[Guar is grown to produce gum that is used in the oil and gas industry for various well treatment procedures to increase production of oil and gas from a well.&nbsp; A variety of guar developed at Texas Tech University has significantly higher seed yield than other variety and a higher gum content when compared to commercial cultivars currently grown in West Texas.&nbsp; Guar is drought resistant and grows well in dry conditions.&nbsp; &nbsp;Reference Number: D-473&nbsp;Market Applications:Oil &amp; Gas Industry&nbsp;Features, Benefits &amp; Advantages:&nbsp; &nbsp; &nbsp; &nbsp;  &nbsp;Offers ...]]></description><pubDate>Fri, 31 Oct 2014 08:50:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17449</guid></item><item><title>Fracturability Index for Optimal Well Placement and Fracture Positioning</title><caseId>D-1105</caseId><link>http://ttusorc.technologypublisher.com/technology/17406</link><description><![CDATA[The early detection of &quot;sweet spots&quot; for oil/gas well site selection and fracturing in shale reservoirs is a challenge for many operators. Most of the time, unique parameters are utilized (i.e. brittleness) to determine the &quot;sweet spots&quot; for well site placement. Additionally, the fractures are generally placed equidistantly. This may create short transverse and/or axial fractures that are problematic during hydraulic fracturing and may create sub-optimal production.&nbsp; &nbsp;This technology utilizes an integrated approach to site selection and fracture sequencing that al...]]></description><pubDate>Tue, 21 Oct 2014 12:53:06 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17406</guid></item><item><title>Passive Structure Wind Energy Extraction System</title><caseId>D-1096</caseId><link>http://ttusorc.technologypublisher.com/technology/17400</link><description><![CDATA[The inventor has designed a fluid flow energy extraction system that requires no external rotor blades. The fundamental principle of the invention is to maximize the generation of high pressure potential in a passive structure. This is done through the design of a self-amplifying aerodynamic system consisting of two or more airfoils.&nbsp; The inventor has developed several embodiments for this concept. &nbsp;Reference Number: D-1096&nbsp;Market Applications:&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Wind Energy Systems&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Tidal Energy Systems&n...]]></description><pubDate>Tue, 21 Oct 2014 12:32:44 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17400</guid></item><item><title>MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer</title><caseId>D-1129</caseId><link>http://ttusorc.technologypublisher.com/technology/17399</link><description><![CDATA[Breast cancer has become the most frequently diagnosed cancer in women, and is the second leading cause of death in women. Although relatively ineffective, Mouse Double Mouse Minute 2 (MDM2) inhibitors blocking the MDM2-p53-binding interphase are currently used for the treatment of advanced breast cancer. This new technology targets a novel direct inhibitor of the MdM2 gene --SP141-- that has shown to possess in vitro and in vivo anti-breast cancer activity, with no seen toxicity. &nbsp;Reference Number: D-1129&nbsp;Market Applications:Cancer DiagnosticsIn Vitro Diagnostics&nbsp;Features, Bene...]]></description><pubDate>Tue, 21 Oct 2014 12:07:37 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/17399</guid></item><item><title>Immunomodulation Using Spores and Pollen Grains</title><caseId>D-0884</caseId><link>http://ttusorc.technologypublisher.com/technology/16034</link><description><![CDATA[This technology provides that pollen grains and plant spores can be very effective biomaterials for achieving oral vaccination.&nbsp; Oral vaccination continues to be one of the &rsquo;holy grails&rsquo; in the field of vaccinology. Oral vaccination is needle-free, child friendly, convenient, painless, amenable to self-administration, and is safer because it eliminates needle stick injuries and eliminates sharp medical waste. However, degradation of vaccine antigens in the acid and enzyme-rich environment of the stomach, and poor uptake of vaccine molecules across the tightly juxtaposed epithe...]]></description><pubDate>Fri, 03 Oct 2014 09:01:16 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16034</guid></item><item><title>Vocal Recognition Speech Signal Processing Extracts Single Voice  </title><caseId>D-0205</caseId><link>http://ttusorc.technologypublisher.com/technology/16030</link><description><![CDATA[This speech signal processing system performs vocal recognition for applications like voice-over-internet protocol (VoIP), medical transcription and hearing aids.&nbsp; The system recognizes vocal patterns and tracks each voice in a group so that an individual's voice can be selected and extracted from background noises and other competing voices.&nbsp;Human speech changes rapidly in pace and pitch over a short period of time. This speech technology tracks each individual voice through time so that the unique sounds and properties of that voice can be reconstructed and presented to the listene...]]></description><pubDate>Thu, 02 Oct 2014 10:32:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16030</guid></item><item><title>Battery Storage with High Energy and Rapid Charge Rates</title><caseId>D-1079</caseId><link>http://ttusorc.technologypublisher.com/technology/16028</link><description><![CDATA[The energy density of a storage device refers to the amount of energy that can be stored within a device of a specific size. Power density refers to the manner in which energy can be stored. The greater the power density, the faster the storage device can be charged and discharged. Typically, batteries have high energy density and low power density while capacitors have low energy density and high power density. Ideally, a storage device will have both high energy density and high power density but, generally speaking, most storage devices achieve only one of these parameters.&nbsp;&nbsp;This ...]]></description><pubDate>Thu, 02 Oct 2014 09:39:50 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16028</guid></item><item><title>Method to Enhance Treatment of Metastatic Melanoma with BRAF Inhibitors</title><caseId>D-1099</caseId><link>http://ttusorc.technologypublisher.com/technology/16024</link><description><![CDATA[Malignant melanoma is the most lethal form of skin cancer and accounts for almost 80% of skin cancer deaths.&nbsp; About 60% of melanomas have a mutation in the BRAF oncogene at V600E.&nbsp; The FDA recently approved (January 2014) the combination of a BRAF inhibitor (Dabrafenib) and a MEK 1/2 inhibitor (Trametinib) to treat this type of melanoma.&nbsp; A problem with this therapy has been the development of cell resistance and and back acquired resistance in many patients.&nbsp; This invention has provided a novel drug combination to overcome this resistance.&nbsp;Reference Number: D-1099&nbs...]]></description><pubDate>Wed, 01 Oct 2014 14:49:05 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16024</guid></item><item><title>Novel Compounds for Treating Patients with Multiple System Atrophy</title><caseId>D-1098</caseId><link>http://ttusorc.technologypublisher.com/technology/16023</link><description><![CDATA[Multiple system atrophy (MSA) is a progressive brain disorder that affects movement and balance and disrupts the function of the autonomic nervous system.&nbsp; This invention utilizes an FDA approved drug to treat MSA.&nbsp; This drug was originally approved for treating relapsing-remitting multiple sclerosis (MS).&nbsp; &nbsp;Reference Number:&nbsp; D-1098&nbsp;Market Applications: &nbsp;Treatment for Multiple System AtrophyPossible treatment for other neurodegenerative diseases.&nbsp;Features, Benefits, &amp; Advantages:Research has shown that this compound (FTY720) turns on neurotrophic fa...]]></description><pubDate>Wed, 01 Oct 2014 14:30:53 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16023</guid></item><item><title>Gene Therapy Vector for Modification for anti HIV Gene Therapy</title><caseId>D-1097</caseId><link>http://ttusorc.technologypublisher.com/technology/16018</link><description><![CDATA[Human immunodeficiency virus (HIV) over time causes acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening, opportunistic infections and cancers to thrive.&nbsp; Cell toxicity is a major problem when treating HIV.&nbsp; This technology has developed a unique gene therapy to help overcome this toxicity. &nbsp;&nbsp;Reference Number: D-1097&nbsp;Features, Benefits &amp; Advantages: This invention is a unique vector for modification of CD34+ hematopoietic stem cells for anti HIV gene therapy. The vector contains a modified ...]]></description><pubDate>Tue, 30 Sep 2014 15:32:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16018</guid></item><item><title>Fast Electrochemical Supercapacitors Based on Vanadium Oxides Core-shell Nanostructure Electrodes</title><caseId>D-1085</caseId><link>http://ttusorc.technologypublisher.com/technology/16005</link><description><![CDATA[Supercapacitors have higher power density than conventional batteries and a higher energy density than regular capacitors. They&nbsp; have proven invaluable for grid energy storage systems, especially with the upcoming intermittent renewable energy sources.&nbsp; This technology has developed a novel transition metal oxide for electrochemical capacitors &lsquo;supercapacitors&rsquo; that is a core-shell nanostructure composed of a vanadium oxide core and an electronically active phase nanoshell.&nbsp;&nbsp;Reference Number:&nbsp; D-1085&nbsp;Market Applications:Transportation, industrial, and ...]]></description><pubDate>Mon, 29 Sep 2014 14:09:17 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16005</guid></item><item><title>Embryo Weight Estimation Based on Specific Gravity</title><caseId>D-1083</caseId><link>http://ttusorc.technologypublisher.com/technology/16004</link><description><![CDATA[This technology is an Assisted Reproduction Technology designed as a specific gravity system that estimates the weight of the embryos for determining the viability of embryos.&nbsp; It is a non-invasive technique that uses specific gravity as an indicator of weight and allows for the heaviest embryos to be selected for implantation.&nbsp; This approach is safe, simple and reliable.&nbsp;&nbsp;Reference Number: D-1083&nbsp;Market Applications:hospitalsfertility clinicsveterinary hospitalsresearch laboratories&nbsp;Features, Benefits and Advantages:This technique is based on the concept that giv...]]></description><pubDate>Mon, 29 Sep 2014 12:41:00 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16004</guid></item><item><title>Synthesis of portable x-ray fluorescence spectrometry and visible near infrared diffuse reflectance spectroscopy for soil chemical characterization</title><caseId>D-1074</caseId><link>http://ttusorc.technologypublisher.com/technology/16003</link><description><![CDATA[Traditionally, time-consuming lab-centered routines that are based on raster sampling and wet chemical analysis are utilized for a comprehensive physicochemical soil analysis. However, these methods are time consuming and highly expensive and, thus, not practical nor convenient for the mapping of soil properties over large areas. &nbsp;The disclosed technology solves this issue by proposing a prototype that will merge data from both the Portable X-Ray Fluorescence and the Visible Near Infrared Diffuse Reflectance Spectroscopy (henceforth referred to as PXRF and VisNIR DRS, respectively), thus ...]]></description><pubDate>Mon, 29 Sep 2014 12:12:23 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/16003</guid></item><item><title>Maximize liquid oil production by huff-n-puff of produced gas in shale gas condensate reservoirs</title><caseId>D-1068</caseId><link>http://ttusorc.technologypublisher.com/technology/15993</link><description><![CDATA[Currently, the standard practice to produce a conventional (high-permeability) gas condensate, is to inject gas and/or water to flood the gas condensate while maintaining the lower bottom-hole flowing pressure above the dew point pressure. However, keeping the flowing pressure above the dew point results in a lower pressure difference between the reservoir and the flowing pressure which negatively impacts oil recovery.&nbsp; Additionally, since formation permeability is low in shale and tight reservoirs, a flooding technique is not feasible because the pressure drop from an injector to a produ...]]></description><pubDate>Fri, 26 Sep 2014 10:30:47 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15993</guid></item><item><title>JNK Inhibitors for Use in Treating Spinal Muscular Atrophy</title><caseId>D-1054</caseId><link>http://ttusorc.technologypublisher.com/technology/15991</link><description><![CDATA[Mutation of the Survival Motor Neuron1 (SMN1) gene causes spinal muscular atrophy (SMA), a progressive neurodegenerative disorder which is the leading cause of infant death in the U.S.&nbsp; Degeneration of spinal motor neurons caused by SMN deficiency results in muscle atrophy and death.&nbsp; The JNK3 pathway mediates neurodegeneration in SMA.&nbsp; JNK3-deficiency or treatment with JNK inhibitors reduces degeneration of neurons caused by low levels of SMN.&nbsp; &nbsp; &nbsp;Reference Number: D-1054&nbsp;Market Applications:PharmaceuticalsHealth Care&nbsp;Features, Benefits &amp; Advantages...]]></description><pubDate>Fri, 26 Sep 2014 09:12:58 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15991</guid></item><item><title>Total Dynamic Productivity Index (TDPI) Maps for Wells Placement Optimization and Reservoir Management Decisions</title><caseId>D-0949</caseId><link>http://ttusorc.technologypublisher.com/technology/15979</link><description><![CDATA[Advanced modeling of reservoir productivity is set to play a key role in the development and management of oil and gas fields. To prevent oil price fluctuation and meet increasing world demand, efficient extraction of petroleum resources is becoming a primary focus of production companies. Detailed modeling to determine well placement, characterize reservoirs, and highlight production areas of varying yields is a valuable asset to field optimization.&nbsp;Reference Number: D-0949&nbsp;Market Applications:&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Productivity Software: Oil and Gas Reservo...]]></description><pubDate>Thu, 25 Sep 2014 09:43:50 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15979</guid></item><item><title>Mechanism of the Ineffectiveness of Panabinostat against Pancreatic Cancer (Solid Malignancies) and Strategies to Increase its Efficacy</title><caseId>D-0917</caseId><link>http://ttusorc.technologypublisher.com/technology/15978</link><description><![CDATA[Emerging evidence suggests that histone deacetylase inhibitors (HDACi) play a significant role in cancer treatment by allowing for the expression of a tumor suppressant gene. However, the inventors have discovered that HDACi also up-regulates the expression of Bcl2 protein, which leads to resistance to chemotherapy in almost every tumor model. Therefore, HDACi treatment has been limited in its ability to treat solid tumors.&nbsp; This technology aims at combining HDACi with Bcl2 inhibitors, to provide treatment for solid tumors.&nbsp;Reference Number: D-0917&nbsp;Market Applications:&bull;&nbs...]]></description><pubDate>Thu, 25 Sep 2014 09:18:19 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15978</guid></item><item><title>Wind Power Education Degree Focused on Renewable Energy, Prepares Students for Wind Power Industry Career</title><caseId>D-0879</caseId><link>http://ttusorc.technologypublisher.com/technology/15976</link><description><![CDATA[The Texas Tech University Wind Energy Bachelor of Science degree program is the only one of its kind in the nation. Rapid growth in the wind energy industry has produced an increase in demand for a well-educated workforce. Texas Tech University, already a pioneer in wind energy education, developed the Bachelor of Science in Wind Energy to meet these expanding needs and educate the future leaders of the wind energy field.&nbsp;Wind energy career training has become increasingly popular, with more than 85,000 wind-energy related jobs currently in place in the United States and more than 300,000...]]></description><pubDate>Thu, 25 Sep 2014 07:32:58 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15976</guid></item><item><title>Method of Manipulating Grape Berry Ripening by Small RNAs</title><caseId>D-0862</caseId><link>http://ttusorc.technologypublisher.com/technology/15975</link><description><![CDATA[Through advanced computer modeling, genes have been discovered that control development of flavonoids in seed producing plants.&nbsp; Flavonoids are involved in plant development, defense against stress, and characteristics such as color, aroma, and flavor.&nbsp; Small RNAs that target these genes can be used to manipulate ripening and nutritional value, especially in grapes. Reference Number: D-0862&nbsp;Market Applications:&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Fruit industry&bull;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Wine industry&nbsp;Features, Benefits, &amp; Advantages:Bioin...]]></description><pubDate>Thu, 25 Sep 2014 07:25:56 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15975</guid></item><item><title>Autonomous Human Motion Monitoring System using Wireless Body-worn Sensors, Network, and Computer-based Algorithms</title><caseId>D-0837</caseId><link>http://ttusorc.technologypublisher.com/technology/15973</link><description><![CDATA[This technology employs a waist-mounted sensor and algorithm that can accurately monitor gait and predict falls. The sensor uses a tri-axial accelerometer to classify gait events into stationary, sit-to-stand or stand-to-sit transitional, walking, running, jumping, and stand-to-kneel or kneel-to-stand transition.&nbsp; The eight tracked features include Energy, Entropy, Mean, Variance, Windowed Mean Difference, Variance trend, etc.&nbsp; These are then implemented in a tree type structure to sort different activities of daily living (ADL).&nbsp; &nbsp;Reference Number: D-0837&nbsp;Market Appli...]]></description><pubDate>Wed, 24 Sep 2014 15:11:45 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15973</guid></item><item><title>New Method for Identification of Cotton Contaminants with X-ray Microtomographic Image Analysis</title><caseId>D-0339</caseId><link>http://ttusorc.technologypublisher.com/technology/15972</link><description>As a natural fiber, cotton is subject to contamination from a variety of sources, including surrounding vegetation, insects, and materials involved in cotton harvesting and handling. The contaminants, which survive the ginning process, have a direct impact on the grade and, hence, the value of the cotton and its derivatives. It is at this stage in the manufacturing process that a precise measurement and identification of the cotton contaminants can improve the accuracy and repeatability of the grading operation. Furthermore, such measurements can provide the necessary feedback for optimizing b...</description><pubDate>Wed, 24 Sep 2014 14:42:14 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15972</guid></item><item><title> Biodiesel Fuel Production using a Continuous, Low Cost Process</title><caseId>D-0581</caseId><link>http://ttusorc.technologypublisher.com/technology/15925</link><description><![CDATA[The invention identifies techniques to overcome the main bottlenecks of the current methods to produce biodiesel; the immiscibility of the two reactants (oil and alcohol), and the need to maintain the reactor temperature below the boiling point of the alcohol.&nbsp; As a consequence of the first bottleneck, the reaction rate is limited by the interfacial surface area between the two reactants, thus requiring large volume reactors.&nbsp; The second bottleneck is imposed to avoid using high-pressure (thus high cost) stirred- tank reactors.&nbsp; Another consequence of the low temperature reactio...]]></description><pubDate>Mon, 22 Sep 2014 14:27:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15925</guid></item><item><title>Use of Thioredoxin or thioredoxin-like molecules, peptides for treatment of high blood pressure</title><caseId>D-1058</caseId><link>http://ttusorc.technologypublisher.com/technology/15924</link><description><![CDATA[A natural protein has been discovered that is effective in controlling blood pressure.&nbsp; Overexpression of the protein was found to&nbsp; lower blood pressure and inhibit the induction of angiotensin II mediated hypertension in mice.&nbsp; Further study showed that the&nbsp; mice, while treated with angiotensin II, had significantly higher relaxation of the mesenteric arteries Thus, this natural protein or its derivatives could be used to control hypertension and pulmonary hypertension.&nbsp; The protein may provide a safer and healthier therapeutic with fewer side effects than existing dr...]]></description><pubDate>Mon, 22 Sep 2014 13:33:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15924</guid></item><item><title>Self-Deployed Cuff and Skirt Tracheal Tube</title><caseId>D-1057</caseId><link>http://ttusorc.technologypublisher.com/technology/15921</link><description><![CDATA[The invention is a self-deployed endotracheal tube using a combined cuff and skirt approach that solves many of the problems associated with traditional endotracheal tubes. This invention replaces the inflation conduit with a hole connecting the inside of the tracheal tube to the inside of the cuff.&nbsp; It also includes a deployable skirt just proximal to and draped over the cuff.&nbsp; When positive pressure is applied to the tracheal tube during inspiration, the cuff is inflated, pressing it against the trachea and deploying the skirt.&nbsp;In expiration, positive end expiratory pressure (...]]></description><pubDate>Mon, 22 Sep 2014 12:35:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15921</guid></item><item><title>Hybrid Mode Wireless Sensor for Tag-less Indoor Human-Oriented Localization and Identification</title><caseId>D-1047</caseId><link>http://ttusorc.technologypublisher.com/technology/15920</link><description><![CDATA[Advances in Radio Frequency Identification (RFID) devices have allowed sensors or tags to be placed on devices, animals, or even human subjects for tracking or other purposes. There have also been recent advancements to develop a tag-less sensor for the identification and localization of human subjects.&nbsp; This invention consists of a tag-less indoor human-oriented localization and identification sensor that accurately localizes human subjects through its dual mode capabilities. &nbsp;Reference Number:&nbsp; D-1047&nbsp;Market Applications:The technology can be applied for the following mar...]]></description><pubDate>Mon, 22 Sep 2014 12:06:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15920</guid></item><item><title>Overcoming Vemurafinib Resistance in Metastatic Melanoma by inhibiting Mcl-1</title><caseId>D-1046</caseId><link>http://ttusorc.technologypublisher.com/technology/15885</link><description>Malignant melanoma is the deadliest form of skin cancer, accounting for seventy-five percent of skin cancer related deaths. Until recently, treatment options for late stage metastatic cancer had been limited. In 2011, the FDA approved vemurafenib, a BRAF inhibitor, for the treatment of late stage metastatic cancer that bears the BRAF oncogene. Patients treated with vemurafenib have showed tumor regression and improved survival; unfortunately, many of the patients later relapse with lethal, drug resistant melanoma, and the mechanism of this resistance remains unknown. The invention relates to a...</description><pubDate>Tue, 16 Sep 2014 15:30:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15885</guid></item><item><title>Internal Bone Lengthener by Plate and Screws</title><caseId>D-1032</caseId><link>http://ttusorc.technologypublisher.com/technology/15883</link><description><![CDATA[The disclosed invention represents a new approach to surgical leg lengthening using an internal device that does not require nailing. The invention consists of a telescoping plate that attaches to the upper and lower portions of the bone via screw; a small motor will be affixed on or within the plate. This motor, controlled remotely, will lengthen the plate, thus lengthening the bone. A ratchet system is used as the expansion mechanism.&nbsp;This device represents a leap in viable treatment for leg lengthening in children. Currently, leg lengthening in children can only be accomplished by exte...]]></description><pubDate>Tue, 16 Sep 2014 14:10:02 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15883</guid></item><item><title>Broad Spectrum Vaccine against Influenza and Anthrax</title><caseId>D-1030</caseId><link>http://ttusorc.technologypublisher.com/technology/15882</link><description><![CDATA[Influenza virus is a prominent seasonal pathogen with the potential to break out into pandemic disease.&nbsp; Despite the availability of current seasonal influenza vaccines, the virus mutates rapidly and necessitates annual re-formulation of vaccines.&nbsp; Anthrax, conversely, is a disease that may be prevented with a single regimen of anti-anthrax vaccine injections. Like influenza virus, the anthrax bacterium remains at the forefront of possible bioterroristic agents, and the associated vaccine is vulnerable to improvement.&nbsp;&nbsp;Here, a vaccine is described which stimulates a broadly...]]></description><pubDate>Tue, 16 Sep 2014 12:40:16 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15882</guid></item><item><title>A Microneedle-mediated and Nanoparticle Adjuvanted Skin Patch Genetic Vaccine against Botulism</title><caseId>D-1020</caseId><link>http://ttusorc.technologypublisher.com/technology/15869</link><description><![CDATA[A pain-free, easily administered and stored vaccine for protection against botulism has been developed. Administration, through the skin, using a micro-needle elicits a stronger immune response than commonly used, and frequently painful, intramuscular injections. The use of a DNA plasmid makes the vaccine quick and simple to manufacture. Together, the DNA plasmid along with the vaccination method, make the vaccine ideal for mass vaccination programs because it is easy to manufacture, administer, store, transport, and seems to be more efficacious than previous vaccines. &nbsp;Reference Number: ...]]></description><pubDate>Fri, 12 Sep 2014 12:38:30 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15869</guid></item><item><title>Pigment Epithelium-Derived Factor Gene-Modified Macrophages to Treat Prostate Cancer</title><caseId>D-1004</caseId><link>http://ttusorc.technologypublisher.com/technology/15867</link><description><![CDATA[Prostate Cancer is the second leading cancer-related death in men. While earlier stages are more easily treated, later stage prostate cancer is extremely aggressive. A method has been developed to genetically modify a patient&rsquo;s immune cells with a noted inhibitor (PEDF) of prostate cancer cell growth. Through this method, incurable, late-stage Castration-Refractory Prostate Cancer (CRPC) can be directly targeted. Additionally, treatment with this method could reduce the use of toxic chemotherapeutic agents, with the aim of improving patient quality of life, while prolonging patient survi...]]></description><pubDate>Fri, 12 Sep 2014 11:49:46 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15867</guid></item><item><title>Use of Lactic Acid and other Probiotic Bacteria to Reduce Pathogens in Lymph Nodes and other Lympatic tissues of Livestock Animals</title><caseId>D-0932</caseId><link>http://ttusorc.technologypublisher.com/technology/15858</link><description><![CDATA[A specific strain of Lactobacilli, NP51 combined with a Propionibacterium, PF24 may be added to cattle feed to improve animal performance and treat E. coli O157.&nbsp; The invention has also been shown to reduce the presence of Salmonella in the lymph nodes of cattle at harvest.&nbsp; Additionally, this product may also be used in dairy cattle and swine to reduce the presence of Salmonella in the lymph nodes and other lymphatic tissues.&nbsp;Reference Number:&nbsp; D-0932&nbsp;Market Applications:This technology is of interest to the food technology and food safety industries.&nbsp; As long as...]]></description><pubDate>Thu, 11 Sep 2014 10:10:34 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15858</guid></item><item><title>A Bacterial Challenge Model in Cattle Using a Trans and intra-dermal Route to Infect Peripheral Lymph Nodes</title><caseId>D-0930</caseId><link>http://ttusorc.technologypublisher.com/technology/15857</link><description><![CDATA[Various Salmonella strains are common food born microbes that cause disease in humans and animals. Some strains can cause intestinal infections, while others cause typhoid fever. Because of the large variety of Salmonella strains present and the different pathogenic effects of these strains, it is important to develop methods capable of observing salmonella within the lymph nodes of cattle and other food sources. This technology can accurately model the duration of a Salmonella infection in the lymph nodes and evaluate potential intervention strategies to reduce the duration of an infection.&n...]]></description><pubDate>Thu, 11 Sep 2014 09:09:27 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15857</guid></item><item><title>Detection and Enumeration Method for Lactobacillus NP51 using culture and molecular techniques</title><caseId>D-0929</caseId><link>http://ttusorc.technologypublisher.com/technology/15856</link><description><![CDATA[A method to both detect and quantify NP51 in animal feeds, foods and fecal samples as well as other environmental samples has been developed.&nbsp; The protocol combines traditional culture methods with molecular methods to detect a very specific strain of industrial importance to the food and feed industries.&nbsp;  Additionally the use of a unique primer to specifically detect NP51 allows for the first method to both detect and quantify NP51 in feed, food and environmental samples.&nbsp;Reference Number: D-0929&nbsp;Market Applications:&bull;&nbsp;&nbsp;&nbsp;&nbsp;Food and feed industries&n...]]></description><pubDate>Thu, 11 Sep 2014 08:46:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15856</guid></item><item><title>CRM1 inhibitors as an adjuvant therapy for lung cancer</title><caseId>D-0928</caseId><link>http://ttusorc.technologypublisher.com/technology/15843</link><description><![CDATA[Lung cancer is the leading cause of cancer deaths worldwide, in part because of chemo-resistance. Using a combination therapy with a novel CRM1 inhibitor has shown to prolong survival for lung cancer. Research has shown very low doses of the inhibitor administered with traditional chemotherapeutic agents reduce toxicity effects compared to other treatments, while extending survival.&nbsp; &nbsp;Reference Number: D-0928 &nbsp;Market Applications:Therapeutics&nbsp;Features, Benefits, and Advantages: The novel addition of CRM1 (chromosome maintenance region 1) inhibitors, to current treatment reg...]]></description><pubDate>Wed, 10 Sep 2014 15:38:06 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15843</guid></item><item><title>A New Universal Influenza Vaccine</title><caseId>D-0923</caseId><link>http://ttusorc.technologypublisher.com/technology/15842</link><description><![CDATA[Contemporary vaccination against the influenza virus has the distinct limitation of transient effectiveness due to the phenomenon of periodic antigenic shift by which the virus mutates to outpace vaccination. However, by targeting a different, more conserved (unchanging) area of the virus, a universal vaccine may be produced that does not need to be updated seasonally.&nbsp;While a universal vaccine is desirable, it has been difficult to create a vaccine that elicits an immune response for the conserved domain of the virus. By this technology&rsquo;s fusion of a mucosal adjuvant with the highl...]]></description><pubDate>Wed, 10 Sep 2014 14:14:23 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15842</guid></item><item><title>RNAi-based New Therapeutic Strategies against Anthrax</title><caseId>D-0885</caseId><link>http://ttusorc.technologypublisher.com/technology/15841</link><description><![CDATA[This therapeutic strategy is directed to the use of small interfering RNAs that target host factors, namely anthrax toxin receptors ANTXR1 and ANTXR2. The reduction of expression of ANTXR1 and ANTXR2 leads to the inhibition of endocytosis of anthrax toxins, which is a significant part of the toxicity mechanism.&nbsp; Furthermore, this strategy uses RNA interference to target proinflammatory cytokine expression in macrophages to prevent anthrax-toxin-induced shock.&nbsp; When used in combination with current antibiotics, this technology would improve anthrax treatment in patients who have alrea...]]></description><pubDate>Wed, 10 Sep 2014 13:11:00 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15841</guid></item><item><title>FTY720 (fingolimod) forms as therapy for neurodegenerative synucleinopathies, including Parkinson's Disease</title><caseId>D-0882</caseId><link>http://ttusorc.technologypublisher.com/technology/15840</link><description><![CDATA[FTY720 (fingolimod) is an anti-inflammatory compound that regulates sphingosine-1 posphate receptors (S1P1) (Hiestand et al., 2008, Miron et al., 2008, Czech et al., 2009).&nbsp; FTY720 has been used in research to treat various health conditions, ranging from stoke and cancer to multiple sclerosis.&nbsp; The compound has been shown to regulate the activity of a major serine/threonine phosphatase PP2A (Perrotti and Neviani, 2008).&nbsp; In September 2010, FTY720 was approved by the FDA for the treatment of Multiple Sclerosis (MS), another condition in which alpha-synuclein is implicated (Papad...]]></description><pubDate>Wed, 10 Sep 2014 12:31:57 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/15840</guid></item><item><title>Schisto Vaccine</title><caseId>D-0696</caseId><link>http://ttusorc.technologypublisher.com/technology/11899</link><description>Schistosomiasis Vaccine for Tropical Disease Bilharzia
Schistosomiasis, known as snail fever or bilharzia, is a tropical disease caused by several types of parasites called schistosomes that infest open bodies of water. A scistosoma vaccine has been developed that could help eradicate this parasitic disease and save millions of lives.
Snail fever is second only to malaria in terms of its devastating social, economic, and public health impact in tropical and subtropical regions of the world.
Children acquire the schistosomiasis disease by swimming in infected water where the parasitic larvae sh...</description><pubDate>Thu, 21 Feb 2013 14:15:42 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/11899</guid></item><item><title>Influenza Vaccine Based on Synthesized Particles</title><caseId>D-0891</caseId><link>http://ttusorc.technologypublisher.com/technology/11898</link><description>This synthetic flu vaccine, which uses gold nanoparticles as the platform, does not need to be adapted annually, like existing influenza vaccines. Furthermore, it has the potential to be a universal vaccine. 
Influenza vaccines have to be adapted every flu season to follow the shifts of the two antigenic membrane proteins expressed on influenza A viruses: hemagglutinin (HA) and neuraminidase (NA). The influenza A virus does have a stable membrane protein, M2e, but it is small and poorly immunogenic compared to HA and NA. Texas Tech University scientists discovered that conjugating M2e to the s...</description><pubDate>Thu, 21 Feb 2013 13:34:27 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/11898</guid></item><item><title>METHOD FOR ENHANCING FAR FEILD COMPLEXITY IN SUBTERRANEAN FORMATIONS</title><caseId>D-0898</caseId><link>http://ttusorc.technologypublisher.com/technology/11897</link><description><![CDATA[This hydraulic fracturing process, developed by Texas Tech, is a method for enhancing the far field network complexity in subterranean formations by optimizing the placement of fractures along the deviated wellbores.Texas Tech's fracking technique is a modification of the zipper frac that initiates fractures in a staggered pattern.&nbsp;Field tests demonstrate that the modified zipper frac improves the performance of fracturing treatment when compared to the original zipper frac by increasing contact area and eventually enhancing fluid production.Modified zipper fracking takes advantage of con...]]></description><pubDate>Thu, 21 Feb 2013 13:08:43 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/11897</guid></item><item><title>Using objective analysis and dual-Doppler synthesis to document wind turbine inflow and wake flow; flow fields upstream, downstream and within wind farms; power deficits; and enhanced turbulence</title><caseId>D-0902</caseId><link>http://ttusorc.technologypublisher.com/technology/9878</link><description>Wind Farm Turbine Wake and Flow Field Analysis With Dual Doppler 
Wind turbines not only produce power, they produce wakes (like those in water) in the atmosphere downstream from each turbine. The wakes can damage other turbines and decrease the efficiency of the wind farm. 
A Ka-band mobile research dual-Doppler radar system developed by the Texas Tech Wind Science and Engineering Research Center allows wind farm operators and developers to measure turbine wakes, turbulence, and air flow fields created by wind turbine operation. This advancement will help to lower the cost of wind energy thro...</description><pubDate>Mon, 30 Jul 2012 06:46:26 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/9878</guid></item><item><title>Gene-optimized Multidrug Resistance P-glycoprotein</title><caseId>D-0825</caseId><link>http://ttusorc.technologypublisher.com/technology/9869</link><description><![CDATA[Anti-cancer and other drug therapies are affected by the multi-drug resistant protein P-glycoprotein (PGP). Research of the drug is critical to determine its role in allowing anti-cancer drugs and other drug therapies to target diseases in the body.&nbsp; PGP is a plasma-membrane protein that actively extrude anti-cancer agents from the cell interior, decreasing drug accumulation and thus allowing the multidrug-resistant cells to survive in the presence of toxic levels of chemotherapeutic agents.&nbsp; This invention is a better way to produce high volutmes of high quality PGP for conducting r...]]></description><pubDate>Fri, 27 Jul 2012 08:26:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/9869</guid></item><item><title>Detection of Carbon Nanotubes in Biological Samples Through Microwave Induced Heating</title><caseId>D-0880</caseId><link>http://ttusorc.technologypublisher.com/technology/9867</link><description>Carbon Nanotube Concentration Measured in Plants for Nano Pollution, Nanotoxicity
This invention uses microwave heating to detect carbon nanotubes in biological samples, measuring carbon nanotube concentration more effectively than current methods like electron microscopy and Raman spectroscopy.
Carbon nanotubes (CNT's) are made up of carbon atoms arranged in a cylindrical nanostructure. They are among the most widely used carbon-based nanomaterials. Nanotubes can easily penetrate membranes like the cell walls of plants. As a result, carbon nanotubes have enormous potential for use in agricult...</description><pubDate>Fri, 27 Jul 2012 08:26:23 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/9867</guid></item><item><title>Producing Antibodies That Mimic T-Cell Receptors to Aid in Cancer Diagnosis and Treatment.</title><caseId>D-0698</caseId><link>http://ttusorc.technologypublisher.com/technology/9106</link><description><![CDATA[The invention relates to a method of producing antibodies that recognize peptides associated with a tumorigenic or disease state, wherein the peptides are displayed in the context of HLA&nbsp;molecules.&nbsp; These antibodies will mimic the specificity of a T-cell receptor such that the molecules may be used as therapeutic, diagnostic and research agents.&nbsp;&nbsp;Market Applications: This new drug can be used for a variety of applications.&nbsp; The invention is directed to identifying unique target molecules on endothelial cells which outline all blood vessels.&nbsp; These cells may be tar...]]></description><pubDate>Tue, 13 Mar 2012 06:52:24 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/9106</guid></item><item><title>Software-Defined Radar Respiration monitor for Gated Lung Cancer Radiotherapy</title><caseId>D-0827</caseId><link>http://ttusorc.technologypublisher.com/technology/8677</link><description><![CDATA[
Invention Title
Software-defined Radar Respiration Monitor 
for Gated Lung Cancer Radiotherapy
&nbsp;
Executive Summary
Current radiation 
treatment methods for lung cancer, the leading cause of cancer death in the 
United States, are plagued with challenges such as required invasive procedures, 
inaccuracy, high imaging radiation doses, difficult clinical implementation, or 
interference by clothing and chest hair. The present invention addresses and 
overcomes each of these challenges. The technology developed at Texas Tech 
University is a device which uses a radar system to deliver absolu...]]></description><pubDate>Tue, 10 Jan 2012 09:32:09 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/8677</guid></item><item><title>Cotton Promoters</title><caseId>D-0281</caseId><link>http://ttusorc.technologypublisher.com/technology/8491</link><description><![CDATA[
Gossypium 
Hirsutum Tissue-Specific Promoters and their Use
D-0281, 
Dr. Randy Allen

Genetic 
modification of cotton for agronomic traits requires the use of promoters that 
cause the expression of attached genes in specific plant tissues or at certain 
developmental times.&nbsp; This patented 
technology relates to an isolated promoter-effective DNA molecule of Gossypium 
which is operable in embryonic seed tissues and an isolated promoter-effective 
DNA molecule of Gossypium which is operable in chlorophyllous tissues.&nbsp;&nbsp; Use of the promoter-effective DNA 
molecules and methods of...]]></description><pubDate>Tue, 13 Dec 2011 12:13:29 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/8491</guid></item><item><title> Microfluidic Device that Generates Arrays of Droplets with Concentration Gradients</title><caseId>D-0813</caseId><link>http://ttusorc.technologypublisher.com/technology/7623</link><description>The present invention describes a novel microfluidic device that allows high-throughput screening (HTS) for biological analysis including drug discovery, cellular assays, DNA analysis, protein crystallization and biomedical diagnostics. The technology developed at Texas Tech University offers a facile way to generate spatially defined arrays of nanoliter (billionth of a liter) volumes of fluids in an enclosed device with each individual volume containing a unique composition. For example, 384 nanoliter volumes can be arrayed in the device with the concentration of a reagent varying by 100,000 ...</description><pubDate>Thu, 14 Jul 2011 14:36:59 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/7623</guid></item><item><title>Measurement of Cotton Stickiness</title><caseId>D-0292</caseId><link>http://ttusorc.technologypublisher.com/technology/7622</link><description><![CDATA[
Invention Title
Cotton Stickiness Evaluation by means of multi-temperature 
testing
&nbsp;
Executive Summary
The present 
invention relates generally to a method for testing stickiness of cotton using 
multiple temperatures.&nbsp; Cotton 
stickiness results from a cyclical disease problem in the cotton crop. 
Our patented evaluation process gives users an accurate grading system 
for cotton stickiness, which can help growers and spinners accurately identify 
different types of cotton and determine processing problems. Our technology 
trumps other technologies by providing users with key infor...]]></description><pubDate>Thu, 14 Jul 2011 14:33:31 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/7622</guid></item><item><title>Root cause analysis in oscillatory control loops</title><caseId>D-0693</caseId><link>http://ttusorc.technologypublisher.com/technology/7615</link><description><![CDATA[Invention 
Title
Software for analyzing the root cause of oscillatory 
behavior in control loop systems. 
&nbsp;
Executive 
Summary
The invention described is a software based tool for use 
in diagnosing the cause of oscillation in systems using multiple control loops. 
The problem of oscillation in control loop systems leads to millions of dollars 
in additional operating expense for manufacturing plants yearly. Additionally, 
an oscillatory control loop limits the maximum quality achievable by the system. 
This software can detect oscillation in the control loops, and describe the root 
caus...]]></description><pubDate>Thu, 14 Jul 2011 08:58:47 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/7615</guid></item><item><title>Structures and Devices based on Boron Nitride</title><caseId>D-0812</caseId><link>http://ttusorc.technologypublisher.com/technology/7182</link><description><![CDATA[
Invention Title:
A novel method of producing hBN semiconducting deep 
ultraviolet (DUV) photonic materials.
&nbsp;
Executive Summary:
The present invention 
relates to the production of hexagonal boron nitride (hBN) semiconducting 
materials and devices.&nbsp; This novel 
technology has two foreseen applications; 1) Deep ultraviolet light emitting 
devices and deep ultraviolet light sensing devices which will provide orders of 
magnitude higher efficiencies than current state-of-the art.&nbsp; Additionally, this mature technology 
(functional prototype) offers a longer product life and is com...]]></description><pubDate>Wed, 25 May 2011 10:08:21 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/7182</guid></item><item><title>Novel Peptide (LBBI-1) which inhibits Staphylococcus aureus biofilm</title><caseId>D-0542</caseId><link>http://ttusorc.technologypublisher.com/technology/4367</link><description><![CDATA[
LBBI-1 is a plant polypeptide formed by the medicinal plant Gymnema sylvestre.&nbsp; LBBI-1 has been isolated in pure form and tested against different Staphylococcus aureus to determine its anti-biofilm property.&nbsp; LBBI-1 does not affect the growth or viability of bacteria but blocks the synthesis of several virulence factors under in vitro conditions. &nbsp;It prevents the production of a protective polysaccharide matrix by the bacterium that is responsible for bacterial attachment to the medical devices and thus stops the formation of biofilms.&nbsp; 
Market Applications: 
Currently, t...]]></description><pubDate>Mon, 21 Dec 2009 08:26:21 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/4367</guid></item><item><title>Composite body armor, ballistic protective composite shield and method of manufacturing</title><caseId>D-0396</caseId><link>http://ttusorc.technologypublisher.com/technology/4174</link><description><![CDATA[Most body armor available in the market is uncomfortable to wear because it is heavy and made of non-porus materials that do not allow proper air circulation.&nbsp; As a result, the body armor is worn only during emergencies or when there is an immediate threat.&nbsp;Needlepunched technology permits the manufacture of more comfortable ballistic protection shield by interconnecting a non-woven next-to-skin layer (a wear layer) to a layer or multiple layers of anti-ballistic materials, and bonding the anti-ballistic layer to an abrasion resistant layer. The abrasion resistant layer may be leathe...]]></description><pubDate>Mon, 16 Nov 2009 14:14:59 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/4174</guid></item><item><title>Machine vision system for simultaneous evaluation of shrinkage and soil release in fabrics</title><caseId>D-0716</caseId><link>http://ttusorc.technologypublisher.com/technology/4173</link><description>
Soil release corresponds to the efficacy of the fabric in releasing stains after laundering, and shrinkage essentially quantifies the dimensional changes in the fabric post laundering. The invention comprises a machine vision that generates simultaneous, automatic and objective measurements of soil release and shrinkage in fabrics. 
Competitive Advantages
This invention solves the problems of the high level of technician involvement in soil release measurement, which tends to produce subjective and non-repeatable measurements. In addition, AATCC test method 130 that is prescribed for oily sta...</description><pubDate>Mon, 16 Nov 2009 12:55:17 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/4173</guid></item><item><title>Method to genetically engineer improved crop plants for a variety of traits including drought adaptation and disease resistance.</title><caseId>D-0426</caseId><link>http://ttusorc.technologypublisher.com/technology/3446</link><description><![CDATA[
Methods to genetically engineer vegetative traits for stress adaptation and disease resistance by directed expression of abscisic acid-related transcription factors can substantially increase the volume and quality of crops grown under stress. 
Applications
It is estimated that global crop losses due to drought exceed $10 billion annually.&nbsp; Methods to genetically engineer value-added vegetative traits for stress adaptation and disease resistance can substantially increase the volume and quality of products produced in difficult environments. 
Competitive Advantages
Improvement of crop pl...]]></description><pubDate>Thu, 24 Sep 2009 13:48:37 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/3446</guid></item><item><title>Naked Tufted Cotton Seed.</title><caseId>D-0593</caseId><link>http://ttusorc.technologypublisher.com/technology/3409</link><description><![CDATA[
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This invention is the development of a better cotton seed. Genetically, this Upland Cotton Naked Tufted Mutant seed has been genetically enhanced, reducing the formation of linters on the seed coat (fuzz left on the seed after ginning). The incorporation of this mutant seed phenotype into a commercial variety of upland cotton (Gossypium hirsutum L.) reduces seed coat neps (waste from the seed plant ovules), reduces the short fiber content (changing the quality of cloth made from the cotton), and increases oil content of the ginned seed. In addition, this trait will reduce the energy an...]]></description><pubDate>Tue, 08 Sep 2009 08:00:14 GMT</pubDate><author>david.mcclure@ttu.edu</author><guid>http://ttusorc.technologypublisher.com/technology/3409</guid></item></channel></rss>