Search Results - siva+vanapalli

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Label–free, high-throughput holographic screening and enumeration of tumor cells in blood

Technology SummaryCirculating tumor cells (CTCs) are cells that have entered the peripheral blood of cancer patients after having left primary or metastatic tumors. Identifying the presence and assessing the characteristics of these CTCs through liquid biopsies has shown great promise for improving cancer patient care by enabling early cancer detection.Current...

Published: 11/29/2018 | Inventor(s): Siva Vanapalli, Dhananjay Singh, Wei Li, Caroline Ahrens

Keywords(s):

Category(s): Assay, Cancer Diagnostics, Device, Life Sciences, Medical Device, Medical Diagnostic, Pharmaceutical, Therapeutics

NOVOPLATE: Pipette-integrated droplet-based nanoliter-volume well plate for bioassays

With the expansive growth of drug screening and other biological assays, there is a need for technologies that can screen drugs using minimal amounts of the compound volumes. Currently, most multi-well plates and pipetting systems are ubiquitously used for this purpose, but are difficult to scale down for use at the nano-level due to problems of volume...

Published: 9/17/2018 | Inventor(s): Siva Vanapalli, Swastika Bithi, Deepak Solomon

Keywords(s):

Category(s): Device, Assay

Microfluidic Device that Generates Arrays of Droplets with Concentration Gradients

The present invention describes a novel microfluidic device that allows high-throughput screening (HTS) for biological analysis including drug discovery, cellular assays, DNA analysis, protein crystallization and biomedical diagnostics. The technology developed at Texas Tech University offers a facile way to generate spatially defined arrays of nanoliter...

Published: 7/2/2018 | Inventor(s): Siva Vanapalli

Keywords(s):

Category(s): Device, General Chemistry