Search Results - cancer+diagnostics

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Label–free, high-throughput holographic screening and enumeration of tumor cells in blood

Technology SummaryCirculating tumor cells (CTCs) are cells that have entered the peripheral blood of cancer patients after having left primary or metastatic tumors. Identifying the presence and assessing the characteristics of these CTCs through liquid biopsies has shown great promise for improving cancer patient care by enabling early cancer detection.Current...

Published: 11/29/2018 | Inventor(s): Siva Vanapalli, Dhananjay Singh, Wei Li, Caroline Ahrens

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Category(s): Assay, Cancer Diagnostics, Device, Life Sciences, Medical Device, Medical Diagnostic, Pharmaceutical, Therapeutics

V2 Pharmacoperone

This invention reports pharmacoperones for their novel use of therapeutics in the treatment of nephrogenic diabetes insipidus (NDI). Pharmacoperones are small molecules that enter the cell and serve as a scaffolding to allow mutated proteins to route correctly. In NDI, there is a mutation in the V2 receptor protein. Here, the inventor has reported over...

Published: 7/2/2018 | Inventor(s): Michael Conn

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Category(s): Cancer Diagnostics

Gene-optimized Multidrug Resistance P-glycoprotein

Anti-cancer and other drug therapies are affected by the multi-drug resistant protein P-glycoprotein (PGP). Research of the drug is critical to determine its role in allowing anti-cancer drugs and other drug therapies to target diseases in the body. PGP is a plasma-membrane protein that actively extrude anti-cancer agents from the cell interior, decreasing...

Published: 8/30/2018 | Inventor(s): Ina Urbatsch

Keywords(s):

Category(s): Cancer Diagnostics