Search Results - junwei+li

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Label–free, high-throughput holographic screening and enumeration of tumor cells in blood

Technology SummaryCirculating tumor cells (CTCs) are cells that have entered the peripheral blood of cancer patients after having left primary or metastatic tumors. Identifying the presence and assessing the characteristics of these CTCs through liquid biopsies has shown great promise for improving cancer patient care by enabling early cancer detection.Current...

Published: 11/29/2018 | Inventor(s): Siva Vanapalli, Dhananjay Singh, Wei Li, Caroline Ahrens

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Category(s): Assay, Cancer Diagnostics, Device, Life Sciences, Medical Device, Medical Diagnostic, Pharmaceutical, Therapeutics

New live attenuated viral vaccine created by self-attenuation with species-specific artificial microRNA

The technology proposes a solution to the potential risks of the current Live Attenuated Influenza Vaccines (LAIV) by proposing a new mammalian-specific LAIV. This was done through the creation of a genetically-engineered influenza virus, that produces an immune response only in mammals. This attenuated vaccine produces mature and functional artificial...

Published: 11/29/2018 | Inventor(s): Mingtao Zeng, Junwei Li

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Category(s): Vaccines

Broad Spectrum Vaccine against Influenza and Anthrax

Influenza virus is a prominent seasonal pathogen with the potential to break out into pandemic disease. Despite the availability of current seasonal influenza vaccines, the virus mutates rapidly and necessitates annual re-formulation of vaccines. Anthrax, conversely, is a disease that may be prevented with a single regimen of anti-anthrax vaccine...

Published: 12/13/2018 | Inventor(s): Mingtao Zeng, Maria Arevalo, Junwei Li

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Category(s): Life Sciences-> Vaccines

A Microneedle-mediated and Nanoparticle Adjuvanted Skin Patch Genetic Vaccine against Botulism

A pain-free, easily administered and stored vaccine for protection against botulism has been developed. Administration, through the skin, using a micro-needle elicits a stronger immune response than commonly used, and frequently painful, intramuscular injections. The use of a DNA plasmid makes the vaccine quick and simple to manufacture. Together, the...

Published: 7/2/2018 | Inventor(s): Mingtao Zeng, Zhengroung Cui, Amit Kumar, Junwei Li

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Category(s): Vaccines

A New Universal Influenza Vaccine

Contemporary vaccination against the influenza virus has the distinct limitation of transient effectiveness due to the phenomenon of periodic antigenic shift by which the virus mutates to outpace vaccination. However, by targeting a different, more conserved (unchanging) area of the virus, a universal vaccine may be produced that does not need to be...

Published: 11/29/2018 | Inventor(s): Mingtao Zeng, Junwei Li

Keywords(s):

Category(s): Vaccines