Search Results - immunology

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Using glycoside hydrolases to treat biofilm-associated infections

Chronic wounds create large healthcare costs and complicate patient healing. Biofilms are a recurring cause of such wounds due to their resilience to antibiotics. Currently, there are no outstanding treatments. The standard of care is debridement followed by antibiotics, however these infections can be hard to treat because of the biofilms. This is...

Published: 9/18/2018 | Inventor(s): Kendra Rumbaugh, Derek Fleming

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Category(s): Antibiotic, Immunology, Life Sciences, Pharmaceutical, Therapeutics

New self-attenuated prophylactic and therapeutic vaccines against microbial pathogens such as influenza viruses.

Technology SummaryTypically live-attenuated viruses alter the viral genome by deletions or mutations that render the virus inert. This is a live-attenuated vaccine for influenza that incorporates microRNA's into the viral genome to attenuate viral replication. This is shown to be beneficial for several reasons including: a robust immune response, another...

Published: 9/18/2018 | Inventor(s): Mingtao Zeng, Ke Wen

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Category(s): Vaccines, Life Sciences-> Vaccines, Immunology, Life Sciences, Therapeutics

Pollen grains for treatment of peanut and other allergies

Peanut allergy is a life-threatening condition that affects approximately 3 million people in the United States. It is typically diagnosed early in life, and only 20% of children outgrow their allergy. Currently, there are no FDA approved methods of treatment, so those affected must avoid peanut products entirely and carry an epinephrine injection in...

Published: 12/6/2018 | Inventor(s): Harvinder Gill, Akhilesh Shakya

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Category(s): Immunology

A biocompatible particle to detect and confirm molecules reactive against the peptide/HLA complex and HLA class I/II molecules

The human leukocyte antigen (HLA) is composed of class I and II complexes, which are expressed by nucleated cells in the body. The HLA class system uses specific peptides in order to inform the immune system of the cell's health status. In the case of an abnormal event (e.g., cancer), immunologically-related molecules such as antibodies or lymphocytes...

Published: 7/2/2018 | Inventor(s): Jon Weidanz, Devin Lowe, Oriana Hawkins

Keywords(s): Antibody, Biomarker, Biotech, Diagnostics, Immunology, polymers

Category(s): Immunology

Gene Therapy Vector for Modification for anti HIV Gene Therapy

Human immunodeficiency virus (HIV) over time causes acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening, opportunistic infections and cancers to thrive. Cell toxicity is a major problem when treating HIV. This technology has developed a unique gene therapy to help overcome...

Published: 11/28/2018 | Inventor(s): Anjali Joshi, Himanshu Garg

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Category(s): Immunology, Pharmaceutical, Therapeutics, Life Sciences