Search Results - himanshu+garg

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Selectable stem cell modification for anti-HIV gene therapy using transient cell surface marking of modified cells using Modified CD4 molecule (CD4mod)

Green fluorescent protein (GFP) is a common in vitro cell surface marker, however, when incorporated in vivo, it can lead to unwanted immune responses. This ultimately leads to their elimination by the immune system. The current technology uses modified CD4 as a cell surface marker to purify modified stem cells using immunomagnetic beads. This method...

Published: 10/11/2018 | Inventor(s): Himanshu Garg, Anjali Joshi

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Category(s): Therapeutics, Life Sciences

Development of Virus like particle (VLP) vaccine and reporter assay for ZIKA virus

The Zika virus outbreaks throughout the world have prompted an immediate need for a vaccine. Currently, there is not an approved vaccine to treat Zika and application of DNA based vaccines has posed severe risks, such as insertional mutagenesis. Due to these threats, the FDA is unlikely to approve DNA based vaccines.This invention has identified a...

Published: 11/29/2018 | Inventor(s): Himanshu Garg, Anjali Joshi

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Category(s): Therapeutics, Assay, Vaccines

Gene Therapy Vector for Modification for anti HIV Gene Therapy

Human immunodeficiency virus (HIV) over time causes acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening, opportunistic infections and cancers to thrive. Cell toxicity is a major problem when treating HIV. This technology has developed a unique gene therapy to help overcome...

Published: 11/28/2018 | Inventor(s): Anjali Joshi, Himanshu Garg

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Category(s): Immunology, Pharmaceutical, Therapeutics, Life Sciences