Search Results - jon+weidanz

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A biocompatible particle to detect and confirm molecules reactive against the peptide/HLA complex and HLA class I/II molecules

The human leukocyte antigen (HLA) is composed of class I and II complexes, which are expressed by nucleated cells in the body. The HLA class system uses specific peptides in order to inform the immune system of the cell's health status. In the case of an abnormal event (e.g., cancer), immunologically-related molecules such as antibodies or lymphocytes...

Published: 7/2/2018 | Inventor(s): Jon Weidanz, Devin Lowe, Oriana Hawkins

Keywords(s): Antibody, Biomarker, Biotech, Diagnostics, Immunology, polymers

Category(s): Immunology

Producing Antibodies That Mimic T-Cell Receptors to Aid in Cancer Diagnosis and Treatment.

The invention relates to a method of producing antibodies that recognize peptides associated with a tumorigenic or disease state, wherein the peptides are displayed in the context of HLA molecules. These antibodies will mimic the specificity of a T-cell receptor such that the molecules may be used as therapeutic, diagnostic and research agents. Market...

Published: 7/2/2018 | Inventor(s): Ulrich Bickel, Jon Weidanz

Keywords(s):

Category(s): Pharmaceutical