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New self-attenuated prophylactic and therapeutic vaccines against microbial pathogens such as influenza viruses.

Technology SummaryTypically live-attenuated viruses alter the viral genome by deletions or mutations that render the virus inert. This is a live-attenuated vaccine for influenza that incorporates microRNA's into the viral genome to attenuate viral replication. This is shown to be beneficial for several reasons including: a robust immune response, another...

Published: 9/18/2018 | Inventor(s): Mingtao Zeng, Ke Wen

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Category(s): Vaccines, Life Sciences-> Vaccines, Immunology, Life Sciences, Therapeutics

Broad Spectrum Vaccine against Influenza and Anthrax

Influenza virus is a prominent seasonal pathogen with the potential to break out into pandemic disease. Despite the availability of current seasonal influenza vaccines, the virus mutates rapidly and necessitates annual re-formulation of vaccines. Anthrax, conversely, is a disease that may be prevented with a single regimen of anti-anthrax vaccine...

Published: 12/13/2018 | Inventor(s): Mingtao Zeng, Maria Arevalo, Junwei Li

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Category(s): Life Sciences-> Vaccines

Schisto Vaccine

Schistosomiasis Vaccine for Tropical Disease Bilharzia Schistosomiasis, known as snail fever or bilharzia, is a tropical disease caused by several types of parasites called schistosomes that infest open bodies of water. A scistosoma vaccine has been developed that could help eradicate this parasitic disease and save millions of lives. Snail fever is...

Published: 9/19/2018 | Inventor(s): Afzal Siddiqui

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Category(s): Life Sciences-> Vaccines