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Pharmacophore elucidatin of phosphodynine A - Potent and selective Peroxisome Prolferator-Activated Receptor agonists with neuroprotective activity

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors and ligand-activated transcription factors that play significant roles in cellular processes. Some isoforms have been validated as therapeutic targets in certain diseases. The role of isoform PPARdelta has not yet been fully explored due to its ubiquitous expression....

Published: 7/2/2018 | Inventor(s): Paul Trippier, Paul Webb

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Category(s): Life Sciences