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Method to Enhance Treatment of Metastatic Melanoma with BRAF Inhibitors
Malignant melanoma is the most lethal form of skin cancer and accounts for almost 80% of skin cancer deaths. About 60% of melanomas have a mutation in the BRAF oncogene at V600E. The FDA recently approved (January 2014) the combination of a BRAF inhibitor (Dabrafenib) and a MEK 1/2 inhibitor (Trametinib) to treat this type of melanoma. A problem...
Published: 7/2/2018
|
Inventor(s):
Sanjay Srivastava
,
Neel Fofaria
Keywords(s):
Cancer
,
Medicine
,
Molecular Medicine
,
Therapeutics
Category(s):
Cancer Therapeutics
,
Pharmaceutical
,
Therapeutics