A Bacterial Challenge Model in Cattle Using a Trans and intra-dermal Route to Infect Peripheral Lymph Nodes

Description:

Various Salmonella strains are common food born microbes that cause disease in humans and animals. Some strains can cause intestinal infections, while others cause typhoid fever. Because of the large variety of Salmonella strains present and the different pathogenic effects of these strains, it is important to develop methods capable of observing salmonella within the lymph nodes of cattle and other food sources. This technology can accurately model the duration of a Salmonella infection in the lymph nodes and evaluate potential intervention strategies to reduce the duration of an infection.

 

Reference Number: D-0930

 

Market Applications:

The technology would be of interest to the food technology and food safety industries.  As long as risks to food safety

exist, efficient diagnostic methods will be in demand.  This technology provides an efficient and robust approach to identifying and differentiating Salmonella serotypes that can cause intestinal infections and typhoid fever when consumed.

 

Features, Benefits, & Advantages:

•       Reliable and consistent results in infections of peripheral lymph nodes in cattle

•       Accurate model created to monitor the duration of infection within the lymph nodes

 

Intellectual Property:

A U.S. utility application, 14,196,582 was filed on 03/04/2014.

 

Development Stage:

This technology has been produced and tested.  Research program is active and ongoing.

 

Researchers:

Guy Loneragan, Professor, Department of Animal and Food Sciences, Texas Tech University

Thomas Edrington, United States Department of Agriculture, Agricultural Research Service

 

Keywords:

•       Salmonella

•       Infection

•       Challenge model

•       Intra-dermal inoculation

•       Trans-dermal inoculation

•       Cattle

 

Patent Information:
Category(s):
Food Science
For Information, Contact:
David Mcclure
Managing Director of Licensing
Texas Tech Office of Research Commercialization
david.mcclure@ttu.edu
Inventors:
Guy Loneragan
Thomas Edrington
Keywords:
Agriculture
Cattle
Food Safety
Immunology
Vaccine